Results 161 to 170 of about 865,901 (361)

The Swampland Conjecture Bound Conjecture

open access: yes, 2021
I conjecture an upper bound on the number of possible swampland conjectures by comparing the entropy required by the conjectures themselves to the Beckenstein-Hawking entropy of the cosmological horizon. Assuming of order 100 kilobits of entropy per conjecture, this places an upper bound of order $10^{117}$ on the number of conjectures.
openaire   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Generalized nonvanishing conjecture and Iitaka conjecture

open access: yesMathematische Zeitschrift
In this article, we will prove the Generalized Nonvanishing Conjecture holds for threefolds with either $κ>0$ or $q>0$. As a result, we can prove the Iitaka conjecture $C_{n,m}$ holds for $n=7$ if the source space has non-negative Kodaira dimension, if the general fibre has positive Kodaira dimension, or if the base space is not threefold with $κ=
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

On Hecke lifting conjecture for framed knots

open access: yesEuropean Physical Journal C: Particles and Fields
Motivated by an amazing integrality structure conjecture for the U(N) Chern–Simons quantum invariants of framed knots investigated by Mariño and Vafa, a new conjectural formula, named Hecke lifting conjecture, was proposed in Chen et al.
Shengmao Zhu
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

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