Results 271 to 280 of about 865,901 (361)

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Lung Resilience: A Model without a Cause. [PDF]

Am J Respir Crit Care Med
Chaïbi K, Tandjaoui-Lambiotte Y.
europepmc   +1 more source

On the Landis Conjecture for Positive Quasi-linear Operators on Graphs [PDF]

Ujjal Das, Matthias Keller, Yehuda Pinchover   +2 more
openalex   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Hirota, Fay and geometry. [PDF]

Lett Math Phys
Eynard B, Oukassi S.
europepmc   +1 more source

An elementary proof of the bunkbed conjecture for forests [PDF]

Serte Donderwinkel, Joost Jorritsma, Guillem Perarnau   +2 more
openalex   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Understanding Functional Evolution in Orthologs and Paralogs. [PDF]

J Mol Evol
Perez M, Hurm K, Liberles DA.
europepmc   +1 more source

Prime numbers, Goldbach's conjecture, De Polignac's conjecture, Legendre's conjecture, and Landau's conjecture

, 2020
Mohamed Sghiar
openalex   +1 more source

Real part of cycle integrals and conjectures of Kaneko [PDF]

Paloma Bengoechea, Sebastián Herrero, Özlem Imamoğlu   +2 more
openalex   +1 more source