Results 151 to 160 of about 84,313 (308)
Conjugate Gradient Methods for Saddle Point Systems [PDF]
, 1999 Conjugate gradient methods have proved to be very efficient for solving saddle point systems, especially with indefinite preconditioning. These systems are idefinite and have a 2x2 block structure.
Lukšan, Ladislav
core
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Low-complexity signal detection algorithm based on preconditioned conjugate gradient method
Dianxin kexue, 2016 For large-scale multiple-input multiple-output system，minimum mean square error signal detection algorithm is near-optimal but involves matrix inversion，and complexity is growing exponentially.
Hua QU +3 more
doaj +2 more sources
TWO MODIFIED CONJUGATE GRADIENT METHODS AND THEIR APPLICATION TO IMAGE RESTORATION PROBLEMS
Ural Mathematical JournalConjugate gradient methods have significantly contributed to the discovery of minimizes of large-scale unconstrained optimization problems. In this paper, based on the Liu--Storey conjugate gradient method, two modified conjugate gradient methods (named ...
Abd Elhamid Mehamdia +3 more
doaj +1 more source
Open problems in nonlinear conjugate gradient algorithms for unconstrained optimization [PDF]
, 2011 The paper presents some open problems associated to the nonlin- ear conjugate gradient algorithms for unconstrained optimization. Mainly, these problems refer to the initial direction, the conjugacy condition, the step length computation, new formula for
Husna Zayadi
core
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
SUBGRADIENT MINIMIZATION METHOD WITH DESCENT VECTORS CORRECTION BY MEANS OF TRAINING RELATIONS PAIRS
Вестник Кемеровского государственного университета, 2014 The paper introduces a conjugate subgradient method whose descent is corrected by a pair of current training relations. The convergence of the method is proved on strictly convex functions.
V. N. Krutikov, Ya. N. Vershinin
doaj