Results 91 to 100 of about 66,000 (256)

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

An improved preconditioned conjugate gradient method for unconstrained optimization problem with application in Robot arm control

open access: yesEngineering Reports
This work suggests improved conjugate gradient methods for enhancing the efficiency and robustness of the classical conjugate gradient methods. The study modifies the diagonal of the inverse Hessian approximation of the Broyden–Fletcher–Goldfarb–Shanno ...
Lawal Muhammad   +4 more
doaj   +1 more source

NUMERICAL AND CONVERGENCE ANALYSIS OF AN ENHANCED DAI-LIAO METHOD FOR UNCONSTRAINED OPTIMIZATION

open access: yesBarekeng
Iterative algorithms play an important role in mathematical optimization, particularly in solving large-scale unconstrained optimization problems. The conjugate gradient (CG) methods are widely used due to their low memory requirements and efficiency ...
Basim A. Hassan   +2 more
doaj   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni   +19 more
wiley   +1 more source

Development of a Spectral Conjugate Gradient Method for Solving Optimization Problems

open access: yesAl-Rafidain Journal of Computer Sciences and Mathematics
Conjugate gradient methods have been favored to use for their efficiency in solving large-scale unconstrained optimization problems, primarily because of their low memory requirements and exclusive to use the first-order derivative information.
Kamal Jameel Murad, Salah Gazi Shareef
doaj   +1 more source

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie   +8 more
wiley   +1 more source

Adaptive Observer for Coupled Wave PDE and Infinite ODE With Sampled Data and Unknown Input: Application to Brain Hemodynamics Estimation

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView.
This article proposes a convergent adaptive observer for a damped wave PDE and an infinite‐dimensional ODE coupled in cascade using sampled‐in‐space ODE state measurements. The proposed observer estimates the distributed states of the PDE and ODE along with unknown PDE parameters and spatial input.
Zehor Belkhatir   +2 more
wiley   +1 more source

Accelerated computing of dynamic carbon emission factor for large-scale power grid using conjugate gradient squared method with p-norm preconditioner

open access: yesEnergy and AI
Amid the global drive for energy decarbonization, power systems—accounting for over 40% of energy-sector carbon emissions—demand precise dynamic carbon tracking and low-carbon scheduling tools.
Bin Wang   +4 more
doaj   +1 more source

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