Results 101 to 110 of about 573,196 (348)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

A REVIEW ON RECENT STUDIES IN THE AREA OF CONJUGATE HEAT TRANSFER MODELLING IN TRANSFORMERS

open access: yesRudarsko-geološko-naftni Zbornik
The exact position and the value of the hot-spot temperature in a transformer could be estimated by calculation using computational fluid dynamics. However, this approach requires the usage of significant computational resources.
Alen Cukrov   +4 more
doaj   +1 more source

Conjugate Heat Transfer During Viscous Incompressible Liquid Movement in the Cavity Considering its Cooling Through Outer Boundary

open access: yesEPJ Web of Conferences, 2016
The paper presents the numerical simulations of the motion of a viscous incompressible non-isothermal fluid in an open rectangular cavity under conditions of conjugate heat transfer. The hydrodynamic flow pattern of a viscous fluid in the cavity obtained.
Krainov A.V., Arhipov V.A.
doaj   +1 more source

Conjugate heat transfer study of the impact of ‘thermo-swing’ coatings on internal combustion engines heat losses

open access: yes, 2020
To comply with the very strict emissions regulation the automotive industry is succeeding in developing ever more efficient engines, and there is scope for more improvements.
A. Broatch   +3 more
semanticscholar   +1 more source

Algorithmic aspects of transient heat transfer problems in structures [PDF]

open access: yes
It is noted that the application of finite element or finite difference techniques to the solution of transient heat transfer problems in structures often results in a stiff system of ordinary differential equations. Such systems are usually handled most
Haftka, R. T., Kadivar, M. H.
core   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

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