Results 171 to 180 of about 51,658 (311)

A combination typhoid and non-typhoidal Salmonella polysaccharide conjugate vaccine in healthy adults: a randomized, placebo-controlled phase 1 trial. [PDF]

Nat Med
Chen WH, Barnes RS, Sikorski MJ, Datar R, Sukhavasi R, Liang Y, Rapaka RR, Pasetti MF, Sztein MB, Wahid R, Tennant SM, Simon R, Baliban SM, Galen JE, Lees A, Bernshtein B, Alter G, Ella R, Mohan K, Naidu MG, Rao DY, Ella KM, Levine MM.   +22 more
europepmc   +1 more source

Evaluation of a diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae type b vaccine given concurrently with meningococcal group C conjugate vaccine at 2, 3 and 4 months of age [PDF]

, 2006
Nicholas Kitchin, Jo Southern, Rob Morris, Fabienne Hemme, Spencer A. Thomas, Michael Watson, Keith Cartwright, Emma R. Miller   +7 more
openalex   +1 more source

MARPLE: A Proximity‐Triggered CRISPR‐Cas13 Platform for Ultrasensitive Antibody Detection

Advanced Science, EarlyView.
MARPLE is a modular CRISPR‐Cas13 immunoassay that uses antibody‐induced proximity to trigger a toehold‐exchange reaction, releasing an RNA activator for Cas13. This one‐pot, isothermal architecture enables ultrasensitive (femtomolar) and highly specific detection of diverse antibodies, including therapeutic, pathogen‐specific, and cancer‐associated ...
Elena Spezzani, Luca Capelli, Denise Di Lena, Alejandro Chamorro‐Garcia, Rudy Ippodrino, Alessandro Porchetta, Alessandro Bertucci   +6 more
wiley   +1 more source

Association between introduction of 13-valent pneumococcal conjugate vaccine and burden of hospitalized adult pneumococcal disease in Hong Kong - A retrospective database study. [PDF]

Hum Vaccin Immunother
Yu Q, Chui CSL, Yeo SH, Patel D, Lim CTK, Li X, Chan VKY, Yamada E, Sukarom I.   +8 more
europepmc   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Effective strategies for typhoid conjugate vaccine delivery: Health and economic insights from the 2015 Kampala outbreak. [PDF]

PLoS Negl Trop Dis
Lee Y, Salonga PKN, Son C, Jang G, Koh DH, Kim JH, Lee H.   +6 more
europepmc   +1 more source

Substituent‐Based Modulation of Self‐Assembly and Immunogenicity of Amphipathic Peptides

Advanced Science, EarlyView.
This study systematically investigates how positional and subtle changes, such as substituents on the phenyl ring attached to short amphipathic peptides, influence their self‐assembly, fibril morphology, and immunogenic responses. ABSTRACT Self‐assembled peptide‐based biomaterials provide versatile platforms for biomedical uses, featuring customizable ...
Anirban Das, Ushasi Pramanik, Elise M. Brown, Chih‐Yun Liu, Huan Gong, Jonathan Fascetti, Mark Gibson, Samuel Stealey, Silviya P. Zustiak, Cory Berkland, Piyoosh Sharma, Meredith E. Jackrel, Mark A. White, Jai S. Rudra   +13 more
wiley   +1 more source

Immunogenicity of a 20-Valent Pneumococcal Conjugate Vaccine Versus a 13-Valent Vaccine in Infants: A Systematic Review and Meta-Analysis. [PDF]

Vaccines (Basel)
Pacheco-Haro MD, de Arenas-Arroyo SN, Díaz-Goñi V, Velasco-Lucio EJ, Castellares-González CI, Reynolds-Cortez V, Simeón-Prieto A, Ignateva E, Martínez-Vizcaíno V.   +8 more
europepmc   +1 more source

A phase 3 randomized trial of the safety and immunogenicity of 20-valent pneumococcal conjugate vaccine in adults ≥ 60 years of age in Japan, South Korea, and Taiwan

Miwa Haranaka, Joon Young Song, Kuo‐Chin Huang, Richard de Solom, Masako Yamaji, Kathleen McElwee, Mary Kline, Masakazu Aizawa, Yahong Peng, Ingrid L. Scully, Osamu Kogawara, William C. Gruber, Daniel A. Scott, Wendy Watson   +13 more
openalex   +1 more source

Impact of Pneumococcal Conjugate Vaccines on the Incidence of Pneumonia in Hospitalized Children after Five Years of Its Introduction in Uruguay

, 2014
María Hortal, Miguel Estevan, Miguel Meny, Inés Iraola, Hilda Laurani   +4 more
openalex   +2 more sources