Results 241 to 250 of about 1,081,297 (374)

Polysaccharide conjugate vaccine protein carriers as a "neglected valency" - Potential and limitations.

Vaccine, 2017
M. Bröker, F. Berti, J. Schneider, I. Vojtek   +3 more
semanticscholar   +1 more source

Engineering Decavalent, Sperm‐Binding Laminin‐IgG Hybrid Antibodies for Potent Non‐Hormonal Contraception

Advanced Science, EarlyView.
This study investigates a highly multivalent mAb platform fusing Laminin‐511 heterotrimerization domains with Fabs and IgG1‐Fc as a non‐hormonal contraceptive. The most potent molecule ‘LamH10’, possessing 10 Fabs, rapidly achieved >99% reduction in progressively motile sperm at just 33µg per dose in sheep, making the laminin‐IgG hybrid platform the ...
Alison Schaefer, Keiichiro Kushiro, Bhawana Shrestha, Yong Zhu, Alysha Panjwani, Lauren Dawson, Haley Flowers, Kathleen L. Vincent, Samuel K. Lai   +8 more
wiley   +1 more source

Clinical and evidence-based considerations for choosing a pneumococcal conjugate vaccine in India: A narrative review. [PDF]

Hum Vaccin Immunother
Yewale V, Chatterjee P, Marathe SM, Taur S, Sathyanarayanan S.   +4 more
europepmc   +1 more source

Biological and Epidemiological Features of Antibiotic-Resistant Streptococcus pneumoniae in Pre- and Post-Conjugate Vaccine Eras: a United States Perspective

Clinical Microbiology Reviews, 2016
L. Kim, L. McGee, S. Tomczyk, B. Beall
semanticscholar   +1 more source

Rapid‐Turnaround Co‐Administration of mRNA‐Based MHC‐I and MHC‐II‐Restricted Neoantigens Enhances Immune Responses of Antigen‐Specific CD8+ T Cells and Anti‐Cancer Efficacy in Colorectal Cancer

Advanced Science, EarlyView.
Co‐administration with MHC class I‐ and II‐restricted neoantigens encoding mRNA‐based personalized cancer vaccines in a mouse CRC model can induce antigen‐specific immune responses and anti‐cancer effects. Notably, vaccination at an early stage of cancer development can have potent anti‐cancer effects. Furthermore, combining mRNA with immune checkpoint
Seongje Cho, Woori Kwak, Hyunho Yoon, Jisun Lee, Seonghyun Lee, Hyo‐Jung Park, Sohee Jo, Yu‐Sun Lee, Yu‐Jeong Seo, Youngran Cho, Seo‐Hyeon Bae, Subin Yoon, Gahyun Roh, Dahyeon Ha, Ayoung Oh, Eun‐Jin Choi, Soo‐Yeon Lee, Huijeong Choi, Jungmin Kim, Yeeun Lee, Sowon Lee, Sang‐In Park, Dae‐Keun Kim, Jun Chang, Ki Tae Kim, Kwoneel Kim, Jae‐Hwan Nam   +26 more
wiley   +1 more source

Immunogenicity and Safety of the Higher-Valent Pneumococcal Conjugate Vaccine vs the 13-Valent Pneumococcal Conjugate Vaccine in Older Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials. [PDF]

Open Forum Infect Dis
Ngamprasertchai T, Ruenroengbun N, Kajeekul R.   +2 more
europepmc   +1 more source

Murine Immune Response toNeisseria meningitidisGroup C Capsular Polysaccharide: Analysis of Monoclonal Antibodies Generated in Response to a Thymus-Independent Antigen and a Thymus-Dependent Toxoid Conjugate Vaccine [PDF]

, 2000
Pablo A. García-Ojeda, Martha E. Monser, Leonard J. Rubinstein, Harold J. Jennings, Kathryn E. Stein   +4 more
openalex   +1 more source

Developing a Personalized Cancer Nanovaccine Using Coxsackievirus‐Reprogrammed Cancer Cell Membranes for Enhanced Anti‐Tumor Immunity

Advanced Science, EarlyView.
A personalized nanovaccine combining PLGA‐encapsulated heat‐inactivated CVB3 and membranes from CVB3‐infected breast cancer cells stimulates potent antitumor immunity. It reduces immunosuppressive markers, enhances immune activation, and improves survival in vivo.
Amirhossein Bahreyni, Yasir Mohamud, Amrit Singh, Razieh Sadat Banijamali, Jeffrey Tang, Jingchun Zhang, Honglin Luo   +6 more
wiley   +1 more source

Fractional Doses of Pneumococcal Conjugate Vaccine - A Noninferiority Trial. [PDF]

N Engl J Med
Gallagher KE, Lucinde R, Bottomley C, Kaniu M, Suaad B, Mutahi M, Mwalekwa L, Ragab S, Twi-Yeboah L, Berkley JA, Hamaluba M, Karani A, Shangala J, Otiende M, Gardiner E, Mugo D, Smith PG, Tabu C, Were F, Goldblatt D, Scott JAG.   +20 more
europepmc   +1 more source

Worldwide Haemophilus influenzae Type b Disease at the Beginning of the 21st Century: Global Analysis of the Disease Burden 25 Years after the Use of the Polysaccharide Vaccine and a Decade after the Advent of Conjugates

, 2000
Heikki Peltola
openalex   +1 more source