Results 301 to 310 of about 1,081,297 (374)

Synthesis of Chirally Chimeric Protein Nanoparticle Vaccines via Mirror‐Image Spy Chemistry

Angewandte Chemie, EarlyView.
This study illustrates a versatile strategy for creating chirally chimeric protein constructs by merging natural‐chirality (L‐) and mirror‐image (D‐) protein motifs through a combination of L‐sortase‐mediated transpeptidation and D‐SpyStapler‐mediated ligation.
Songzi Kou, Chenbo Sun, Weitao Chen, Hanyu Gao, Fei Sun   +4 more
wiley   +2 more sources

Cost of the typhoid conjugate vaccine introduction through an integrated campaign and follow-on routine immunization in Malawi. [PDF]

Vaccine X
Debellut F, Bello G, Chisema M, Mkisi R, Kamzati M, Pecenka C, Mugisha E.   +6 more
europepmc   +1 more source

Nanoparticles Functionalized with Polymer Brushes for Gene Delivery

Advanced NanoBiomed Research, EarlyView.
The engineering of the next generation gene delivery vectors requires the precise control of the architecture and physicochemical interactions controlling the transport, targeting, uptake, and release of nucleic acid materials to targeted cells. Polymer brush‐functionalized nanomaterials offer unprecedented control over such design and properties, and ...
Carlos E. Neri‐Cruz, Julien E. Gautrot
wiley   +1 more source

Embracing Complexity: Peptides as Tunable Scaffolds in the Construction of Discrete Supramolecular Systems

Angewandte Chemie, EarlyView.
The inherent chirality, tunability, biocompatibility, and robustness of peptides provide an exciting opportunity for supramolecular chemistry. In this mini‐review, we explore uses of peptides in discrete supramolecular systems, how chemists can draw inspiration from larger biological assemblies, and discuss how embracing the complexity of peptide ...
Ben E. Barber, Ellen M. G. Jamieson, Leah E. M. White, Charlie T. McTernan   +3 more
wiley   +2 more sources

Cost-effectiveness analysis of the 13-valent pneumococcal conjugate vaccine administered to children under 5 years of age in the Republic of Moldova. [PDF]

Med Pharm Rep
Balanuta AM, Bujor D, Paraschiv A, Horodisteanu-Banuh A, Revenco N.   +4 more
europepmc   +1 more source

Three Is Better than One: A Multimetal Complex that Triggers Immunogenic Cell Death

Angewandte Chemie, EarlyView.
A triple metal prodrug that codelivers PtII, RuII, and AuI species triggers a potent immunogenic cell death (ICD) response via combined Type I/II pathways. The tri‐metallic scaffold promotes tumor inhibition, immune memory, and peripheral leukocyte activation, offering a next‐generation chemo‐immunotherapeutic approach (created in BioRender.
Tomer Babu, Matthew S. Levine, Sourav Acharya, Esther Y. Maier, Jonathan L. Sessler   +4 more
wiley   +2 more sources

Natural Carriage of Streptococcus pneumoniae Is Associated With Increased Experimental Pneumococcal Carriage but Reduced Conjugate Vaccine Efficacy in a Human Challenge Model. [PDF]

J Infect Dis
Galafa B, Chikaonda T, Kudowa E, Sichone S, Sibale L, Thole F, Mkandawire C, Dula D, Nsomba E, Tembo G, Chaponda M, Chirwa AE, Nkhoma V, Ngoliwa C, Kamng'ona R, Toto N, Makhaza L, Muyaya A, Howard A, Nyazika TK, Ndaferankhande J, Chimgoneko L, Banda NPK, Chiwala G, Rylance J, Ferreira D, Jambo KC, Morton B, Morton B, Henrion MYR, Gordon SB.   +30 more
europepmc   +1 more source

LACK OF PNEUMOCOCCAL ANTIGENURIA IN INFANTS IMMUNIZED WITH HEPTAVALENT PNEUMOCOCCAL CONJUGATE VACCINE

, 2001
Khaled Hilal, R. A. Carey, Malliswari Challapalli   +2 more
openalex   +1 more source

Typhoid Conjugate Vaccine: A Boon for Endemic Regions. [PDF]

Cureus
Agarwal N, Gupta N, Nishant, H S S, Dutta T, Mahajan M.   +5 more
europepmc   +1 more source

Toward optimized carbohydrate-based anticancer vaccines: Epitope clustering, carrier structure, and adjuvant all influence antibody responses to Lewis^yconjugates in mice

, 2001
Valery Kudryashov, Peter W. Glunz, Lawrence J. Williams, Samuel Hintermann, Samuel J. Danishefsky, Kenneth O. Lloyd   +5 more
openalex   +1 more source