Results 111 to 120 of about 46,055 (312)

PIN16 COMPARATIVE CRITICAL REVIEW OF COST-EFFECTIVENESS TOOLS OF PNEUMOCOCCAL CONJUGATE VACCINE (PCV)

, 2010
Nathorn Chaiyakunapruk, Ratchadaporn Somkrua, Raymond Hutubessy, AMH Restrepo, Alessia Melegaro, John Edmunds, Philippe Beutels   +6 more
openalex   +1 more source

Size‐Dependent Ultrasound Activation of Thrombin Catalytic Activity by Mechano‐Nanoswitches

Advanced Science, EarlyView.
The fundamental principles linking nanoparticle (NP) physicochemical properties to their interactions with sonomechanical forces are not well‐defined. This work systematically investigates the size‐dependent ultrasound activation of thrombin using different‐sized mechano‐nanoswitches, which provides critical insights into the role of NP size in nano ...
Menghan Xiao, Zhihuan Liao, Junliang Chen, Xiong Zuo, Jiangting Zeng, Xiangfu Du, Zihao Teng, Johannes Hahmann, Andreas Herrmann, Shuaidong Huo   +9 more
wiley   +1 more source

Potent and Long‐Lasting Immunogenicity Generated by LNP‐mRNA gE Antigen Against Varicella Zoster Virus via an AI‐Assisted Pipeline

Advanced Science, EarlyView.
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong, Fang Liu, Dawei Wang, Yanfen Li, Man Zhang, Yuting Zhou, Gengshen Song   +6 more
wiley   +1 more source

Comparing Haemophilus influenzae Type b Conjugate Vaccine Schedules

, 2013
Nicola Low, Shelagh Redmond, Anne WS Rutjes, Nahara Anani Martínez-González, Matthias Egger, Marcello Di Nisio, Pippa Scott   +6 more
openalex   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Efficacy and effectiveness of extended-valency pneumococcal conjugate vaccines [PDF]

, 2014
Hyunju Lee, Eun Hwa Choi, Hoan Jong Lee
openalex   +1 more source

Paediatric Meningitis in the Conjugate Vaccine Era and Development of a Novel Clinical Decision Model to Predict Bacterial Aetiology in 3,002 Children with Suspected Meningitis

, 2023
Natalie G. Martin, Sylviane Defres, Louise Willis, Rebecca Beckley, Annabel Coxon, Seilesh Kadambari, Ly‐Mee Yu, Xinxue Liu, Ushma Galal, Kerry Conlin, Michael J. Griffiths, Rachel Kneen, Simon Nadel, Paul T. Heath, Dominic F. Kelly, Tom Solomon, Manish Sadarangani, Andrew J. Pollard, UK-ChiMes Study Group, ENCEPH UK Study Group   +19 more
openalex   +1 more source

Nanoparticle Adjuvant Design Enhances Germinal Center Responses Targeting Conserved Subdominant Epitopes for Pan‐Coronavirus Vaccine Development

Advanced Science, EarlyView.
Current SARS‐CoV‐2 vaccines generate short‐lived, strain‐specific immunity. A polymeric TLR7 agonist nanoparticle (TLR7‐NP) adjuvant enhances lymph node targeting and promotes early and sustained germinal center responses toward conserved S2 epitopes of the spike protein.
Sijin Huang, Kanella M. Cohen, Liqiang Chen, Xiaowo Kang, Chang Liu, Megan E. Demouth, Wenxia Jiang, Alexander R. Maldeney, Rong Tong, Zunlong Ke, Kartik Chandran, Wei Luo, Qian Yin   +12 more
wiley   +1 more source

Las vacunas conjugadas contra la enfermedad meningococica causadas por los serogrupos A, C, W-135, Y

VacciMonitor, 2009
Review the current evidence on available and candidate quadrivalent meningococcal conjugate vaccines. Methods: A comprehensive overview of data on the currently available A-C-W135-Y meningococcal vaccine and the results of late stage development of novel
Marcos Aurelio P. Sáfadi
doaj  

Mortality of Invasive Pneumococcal Disease following Introduction of the 13-Valent Pneumococcal Conjugate Vaccine in Greenland [PDF]

Kristiana Alexandrova Nikolova, Mikael Andersson, Hans‐Christian Slotved, Anders Koch   +3 more
openalex   +1 more source