Results 161 to 170 of about 55,913 (304)

GRP78 Nanobody‐Directed Immunotoxin Activates Innate Immunity Through STING Pathway to Synergize Tumor Immunotherapy

Advanced Science, EarlyView.
A GRP78 nanobody‐directed immunotoxin suppresses cancer progression and metastasis by enhancing antitumor immunity via STING pathway activation, offering a pan‐cancer‐targeted approach and immunotherapy combination strategy. Abstract The lack of targetable antigens poses a significant challenge in developing effective cancer‐targeted therapies.
Huifang Wang, Runhua Zhou, Chengchao Xu, Lingyun Dai, Rui Hou, Liuhai Zheng, Chunjin Fu, Guangwei Shi, Jingwei Wang, Yang Li, Jinpeng Cen, Xiaolong Xu, Le Yu, Yilei Li, Jigang Wang, Qingfeng Du, Zhijie Li   +16 more
wiley   +1 more source

Subclass distribution of IgA antibodies in saliva and serum after immunization withHaemophilus influenzaetype b conjugate vaccines [PDF]

, 1998
M. Kauppi-Korkeila, Leena Saarinen, Juhani Eskola, Helena Käyhty   +3 more
openalex   +1 more source

First characterization of immunogenic conjugates of vi negative salmonella typhi O- specific polysaccharides with rEPA protein for vaccine development [PDF]

, 2016
Efficacious typhoid vaccines for young children will significantly reduce the disease burden in developing world. The Vi polysaccharide based conjugate vaccines (Vi-rEPA) against Salmonella Typhi Vi positive strains has shown high efficacy but may be ...
A, Haque, A. D, Cox, A., Ali, M, Iqbal, M, Rahman, M, Salman   +5 more
core   +1 more source

Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies

Advanced Science, EarlyView.
Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu, Yao Liu, Zujun Que, Bin Luo, Yun Yang, Yan Li, Zhanxia Zhang, Jianhui Tian   +7 more
wiley   +1 more source

The Induction of Immunologic Memory after Vaccination withHaemophilus influenzaeType b Conjugate and Acellular Pertussis–Containing Diphtheria, Tetanus, and Pertussis Vaccine Combination [PDF]

, 1999
David Goldblatt, Peter Richmond, Elena V. Millard, Carol A. Thornton, Emma R. Miller   +4 more
openalex   +1 more source

A conjugate vaccine for typhoid [PDF]

Nature Medicine, 2020
openaire   +3 more sources

Electrical Microneedles for Wound Treatment

Advanced Science, EarlyView.
A review on state‐of‐art research concerning electrical microneedles applied for wound treatment is presented. After a comprehensive analysis of mechanisms of electrical stimulation on wound healing, the derived three types of electrical microneedles are clarified and summarized. Further, their applications in wound healing are highlighted.
Yu Wang, Lijun Cai, Lu Fan, Li Wang, Feika Bian, Weijian Sun, Yuanjin Zhao   +6 more
wiley   +1 more source

Heterogeneous population and its resilience to misinformation in vaccination uptake: A dual ODE and network approach [PDF]

arXiv
Misinformation about vaccination poses a significant public health threat by reducing vaccination rates and increasing disease burden. Understanding population heterogeneity can aid in recognizing and mitigating the effects of such misinformation, especially when vaccine effectiveness is low.
arxiv  

EVALUATION OF A PENTAVALENT CONJUGATED PNEUMOCOCCAL VACCINE IN TODDLERS.▴ 1077 [PDF]

, 1996
Michael E. Pichichero, Mark Shelly, John J. Treanor   +2 more
openalex   +1 more source

Programmable Stapling Peptide Based on Sulfonium as Universal Vaccine Adjuvants for Multiple Types of Vaccines

Advanced Science, Volume 12, Issue 11, March 20, 2025.
A stapling peptide with two sulfonium centers is developed to be used as an excellent vaccine adjuvant candidate for the Hepatitis B vaccine, influenza vaccine, and herpes zoster vaccine. Just by changing the amino acids and ring types, it is easy to program peptide adjuvants to adapt to multiple vaccine subtypes and synergistically induce humoral and ...
Yaping Zhang, Chenshan Lian, Wenlong Lai, Leying Jiang, Yun Xing, Huiting Liang, Jin Li, Xinming Zhang, Jianhui Gan, Zigang Li, Feng Yin   +10 more
wiley   +1 more source