Results 181 to 190 of about 77,026 (328)

Typhoid conjugate vaccines for preventing typhoid fever (enteric fever). [PDF]

Cochrane Database Syst Rev
Gloeck NR, Leong TD, Mthethwa M, Iwu-Jaja CJ, Katoto PD, Wiysonge CS, Kredo T.   +6 more
europepmc   +1 more source

Immunogenicity of synthetic conjugates of Lewis y oligosaccharide with proteins in mice: towards the design of anticancer vaccines

, 1998
Valery Kudryashov, Hyunjin M. Kim, Govindaswami Ragupathi, Samuel J. Danishefsky, Philip O. Livingston, Kenneth O. Lloyd   +5 more
openalex   +2 more sources

Brachyury‐Activated Fucoidan Hydrogel Microspheres Rejuvenate Degenerative Intervertebral Discs Microenvironment

Advanced Science, EarlyView.
This study describes the creation of injectable Brachyury (Bry) mRNA‐loaded Fucoidan‐functionalized GelMA hydrogel microspheres (BLNP@GF). These microspheres efficiently suppress inflammation, enhance extracellular matrix (ECM) synthesis in degenerated nucleus pulposus cells, and mitigate intervertebral disc degeneration (IVDD) in rat models.
Yuhao Gong, Wenxiao Shi, Xingzhu Liu, Hang Yu, Yinghui Wu, Yanzhang Xia, Caichun Yue, Chongkai Yang, Cong Shen, Renjun Pei, Tianwen Xin, Hailong Pei, Jun Shen   +12 more
wiley   +1 more source

The Complex Landscape of Updated Pneumococcal Conjugate Vaccines. [PDF]

Open Forum Infect Dis
Thindwa D, Shapiro ED, Weinberger DM.
europepmc   +1 more source

The Contribution of Specific Pneumococcal Serogroups to Different Disease Manifestations: Implications for Conjugate Vaccine Formulation and Use, Part II [PDF]

, 2000
William P. Hausdorff, John Bryant, C. Kloek, Peter R. Paradiso, George R. Siber   +4 more
openalex   +1 more source

Targeting Neutrophil/Eosinophil Extracellular Traps by Aptamer‐Functionalized Nanosheets to Overcome Recalcitrant Inflammatory Disorders

Advanced Science, EarlyView.
In this study, C‐TAH, as multifunctional nanosheets, is developed with tannic acid and histone aptamer coverage. C‐TAH displays mild cytotoxicity, robust dsDNA and NETs/EETs binding efficiency, and potent antioxidant and antibacterial ability in vitro. C‐TAH treatment ameliorates dysregulated inflammation and restores hearing function in animal models,
Yongqiang Xiao, Xinyue Wang, Ming Liu, Xiao Fu, Nanfeng Zhang, Wenqing Yang, Junyi Ge, Yangyang Li, Duan Ma, Jing Ma, Weiping Wen, Dongdong Ren, Tianyu Zhang, Zhaoxu Tu   +13 more
wiley   +1 more source

Bacterial Acute Otitis Media Complicated with Otorrhea in a Children's Hospital in the Era of Pneumococcal Conjugate Vaccines. [PDF]

Pathogens
Tzovara I, Doudoulakakis A, Kalogeras G, Koutouzis E, Dellis C, Pasparakis S, Charakida M, Lebessi E, Bozavoutoglou E, Tsakanikos M, Syriopoulou V, Tsolia M.   +11 more
europepmc   +1 more source

Engineered Dual‐Function Antibody‐Like Proteins to Combat SARS‐CoV‐2‐Induced Immune Dysregulation and Inflammation

Advanced Science, EarlyView.
Engineered antibody‐like proteins block the SARS‐CoV‐2 spike protein from binding to host receptors and suppress immune overactivation through an MBL‐based scaffold. These dual‐function proteins effectively alleviate inflammation, complement activation, and lung injury, offering a promising therapeutic strategy against severe COVID‐19 and its ...
Yizhuo Wang, Chenwu Bai, Kerui Hou, Zhen Zhang, Ming Guo, Xin Wang, Fan Yang, Xin Liu   +7 more
wiley   +1 more source

Further Insights into the Measurement of Free Polysaccharide in Meningococcal Conjugate Vaccines. [PDF]

Vaccines (Basel)
Beresford NJ, De Benedetto G, Lockyer K, Gao F, Burkin K, Lalwani K, Bolgiano B.   +6 more
europepmc   +1 more source

Covalent Organic Frameworks‐Delivered Reuterin Drives Trained Immunity in Tumor‐Associated Macrophages to Enhance Melanoma Immunotherapy via Glycerophospholipid Metabolism

Advanced Science, EarlyView.
Covalent organic framework (COF)‐reuterin induces trained immunity in tumor‐associated macrophages, promoting the generation of nitric oxide and reactive oxygen species, thereby enhancing the antitumor immune response. Additionally, COF‐Reuterin directly kills tumor cells while simultaneously eradicating pathogenic intratumoural bacteria.
Jian‐Gang Zhang, Xiao‐Mei Zhang, Xi Wu, Cheng‐Kai Zhou, Zhen‐Zhen Liu, Xue‐Yue Luo, Liang Zhang, Wei Chen, Yong‐Jun Yang   +8 more
wiley   +1 more source