Proportion of Invasive Pneumococcal Infections in German Children Preventable by Pneumococcal Conjugate Vaccines [PDF]
Rüdiger von Kries+3 more
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The Economic Case for Expanding Vaccination Coverage of Children [PDF]
While childhood vaccination programs, such as WHO’s Expanded Program on Immunization, have had a dramatic impact on child morbidity and mortality worldwide, lack of coverage with several existing vaccines is responsible for large numbers of child deaths ...
Abigail Friedman+7 more
core
Potent Cross‐neutralizing Antibodies Reveal Vulnerabilities of Henipavirus Fusion Glycoprotein
Hendra and Nipah viruses (HNVs) pose significant threats to global health. This work reports potent cross‐neutralizing antibodies targeting the fusion glycoprotein (F) and reveals shared features of these antibodies and vulnerabilities of F, thereby guiding the rational design of countermeasures against HNVs and similar pathogens.
Yi Ren+19 more
wiley +1 more source
Fragment Autoantigens Stimulated T‐Cell‐Immunotherapy (FAST) as a Fast Autologous Cancer Vaccine
A personalized whole tumor cell vaccine (FAST) is developed to address immunosuppressive tumor microenvironments and genomic instability‐driven heterogeneity. Irradiation and cryoablation‐treated tumor cells generate fragmented antigens (FAs) that activate broad‐spectrum antigen presentation via upregulated immunogenic cell death, MHC‐I, and damage ...
Yuan Li+14 more
wiley +1 more source
An assessment of the value of Haemophilus influenzae type b conjugate vaccine in Asia
Mark A. Miller
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Diagram illustrating the binding methods of NPs and biological barriers. The biological carrier‐mediated nanomedicine hitchhiking strategy (BCM‐NHS) utilizes two distinct techniques: the surface‐based “Backpack” method, which relies on ligand‐receptor binding, covalent conjugation, and non‐covalent binding, and the encapsulated “Trojan horse” approach,
Yuyan Zhou+17 more
wiley +1 more source
Estimation of the indirect effect of Haemophilus influenzae type b conjugate vaccine in an American Indian population [PDF]
Lawrence H. Moulton+5 more
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This study employs neutrophils for the precise delivery of anti‐CD47 antibodies, combined with bacterial outer membrane vesicles, to enhance macrophage phagocytic function in the tumor microenvironment. This approach effectively activates T‐cell anti‐tumor immune responses and significantly reduces the risk of postoperative tumor recurrence and ...
Meng Guan+15 more
wiley +1 more source
Interpreting Results from Trials of Pneumococcal Conjugate Vaccines: A Statistical Test for Detecting Vaccine-induced Increases in Carriage of Nonvaccine Serotypes [PDF]
Marc Lipsitch
openalex +1 more source
A platform for glycoengineering a polyvalent pneumococcal bioconjugate vaccine using E. coli as a host [PDF]
Chavez, Sthefany M.+5 more
core +1 more source