Results 221 to 230 of about 77,026 (328)

Computational design and evaluation of mRNA- and protein-based conjugate vaccines for influenza A and SARS-CoV-2 viruses. [PDF]

J Genet Eng Biotechnol, 2023
Elalouf A, Kedarya T, Elalouf H, Rosenfeld A.   +3 more
europepmc   +1 more source

Keyhole limpet hemocyanin conjugate vaccines against cancer: The Memorial Sloan Kettering experience [PDF]

, 2001
Cristina Musselli, Philip O. Livingston, Govindaswami Ragupathi   +2 more
openalex   +1 more source

Decoy Extracellular Vesicles Overcome Triple‐Negative Breast Cancer Heterogeneity via Membrane‐Cytoplasm‐Mitochondria Cascade Targeting

Advanced Science, EarlyView.
siT/MOF@EVs overcome TNBC heterogeneity through a tumor cell membrane–cytoplasm–mitochondria cascade effect, triggering a self‐reinforcing anti‐tumor immune cycle and durable immune memory. The system enables sequential targeting of membrane checkpoints ligands (decoy effect), cytoplasmic siRNA delivery (CSC suppression), and mitochondrial MOF ...
Chuanrong Chen, Ming Shen, Xiaofeng Wan, Lili Sheng, Na Hao, Man Li, Menglin Xu, Yang He, Jiali Zhang   +8 more
wiley   +1 more source

Correction to: The Complex Landscape of Updated Pneumococcal Conjugate Vaccines. [PDF]

Open Forum Infect Dis
europepmc   +1 more source

Serotype distribution of invasive and non-invasive pneumococcal disease in children ≤5 years of age following the introduction of 10- and 13-valent pneumococcal conjugate vaccines in infant national immunization programs: a systematic literature review. [PDF]

Front Public Health
Izurieta P, AbdelGhany M, Borys D.
europepmc   +1 more source

Personalized Neoantigen Vaccine plus Regorafenib Increases Rgs2⁺CD8⁺ T Cells Infiltration and Reprograms the Tumor Microenvironment in Microsatellite Stable Colorectal Cancer Liver Metastases

Advanced Science, EarlyView.
This study synthesized a personalized neoantigen vaccine (Neo‐CRCVAS) and combined it with regorafenib, termed RegoNeo. This combination therapy significantly enhanced antitumor efficacy and promoted long‐term tumor‐specific immune memory in microsatellite stable colorectal cancer liver metastasis (MSS‐CRLM) models by increasing neoantigen‐specific ...
Hengkai Chen, Bin Chen, Yuanfeng Yang, Shoufeng Li, Huajun Cai, Zhicheng Zhuang, Yong Wu, Yuan Gao, Yupeng Chen, Xing Liu, Guoxian Guan, Jinfu Zhuang   +11 more
wiley   +1 more source

Serotype distribution of invasive and non-invasive pneumococcal disease in adults ≥65 years of age following the introduction of 10- and 13-valent pneumococcal conjugate vaccines in infant national immunization programs: a systematic literature review. [PDF]

Front Public Health
Izurieta P, Borys D.
europepmc   +1 more source

Hyperspectral Imaging Techniques for Lyophilization: Advances in Data‐Driven Modeling Strategies and Applications

Advanced Science, EarlyView.
Lyophilization is a key process used in the production of biotherapeutic products. This article reviews and discusses the application of HSI on lyophilization, and the strategies that use the resulting data to build models. It is intended to provide guidance and insights for non‐specialist researchers and engineers into leveraging HSI and the data ...
Huiwen Yu, Prakitr Srisuma, Cedric Devos, Jie Wang, Allan S. Myerson, Richard D. Braatz   +5 more
wiley   +1 more source

Global impact of 10- and 13-valent pneumococcal conjugate vaccines on pneumococcal meningitis in all ages: The PSERENADE project. [PDF]

J Infect
Yang Y, Knoll MD, Herbert C, Bennett JC, Feikin DR, Garcia Quesada M, Hetrich MK, Zeger SL, Kagucia EW, Xiao M, Cohen AL, van der Linden M, du Plessis M, Yildirim I, Winje BA, Varon E, Valenzuela MT, Valentiner-Branth P, Steens A, Scott JA, Savrasova L, Sanz JC, Khan AS, Oishi K, Nzoyikorera N, Nuorti JP, Mereckiene J, McMahon K, McGeer A, Mackenzie GA, MacDonald L, Ladhani SN, Kristinsson KG, Kleynhans J, Kellner JD, Jayasinghe S, Ho PL, Hilty M, Hammitt LL, Guevara M, Gilkison C, Gierke R, Desmet S, De Wals P, Dagan R, Colzani E, Ciruela P, Chuluunbat U, Chan G, Camilli R, Bruce MG, Brandileone MC, Ampofo K, O'Brien KL, Hayford K, PSERENADE Team.   +55 more
europepmc   +1 more source

Efficacy of a Pneumococcal Conjugate Vaccine against Acute Otitis Media [PDF]

, 2001
Juhani Eskola, Terhi Kilpi, Arto A. Palmu, Jukka Jokinen, Mervi Eerola, Jaason Haapakoski, Elja Herva, Aino K. Takala, Helena Käyhty, P. Karma, Robert Kohberger, Stephen Lockhart, George R. Siber, P. Helena Mäkelä   +13 more
openalex   +1 more source