Results 231 to 240 of about 77,026 (328)

Divergent Delivery and Expression Kinetics of Lipid and Polymeric Nanoparticles across mRNA Modalities

Advanced Science, EarlyView.
Self‐amplifying (saRNA), linear (linRNA), and circular (circRNA) mRNAs are compared under standardized conditions using lipid nanoparticles (LNPs) and pABOL polymer. saRNA achieved superior expression, while linRNA and circRNA performance varied based on untranslated region elements and delivery method.
Irafasha C. Casmil, Josh J. Friesen, Nuthan V. Bathula, Anneke Strumpel, Chia Hao Ho, Ilana Guez, Kristen Y. S. Kong, Andrew J. Varley, Shigeki J. Miyake‐Stoner, Parinaz Aliahmad, Nathaniel S. Wang, Andrew J. Geall, Anna K. Blakney   +12 more
wiley   +1 more source

The lights went out.

, 2012
Cavelaars, Chen, Cholesterol Treatment Trialists' Ctt Collaboration, Kromhout, Kunitz, Leon, S. Ebrahim, Uusitalo   +7 more
core   +1 more source

Use of Capsular Polysaccharide–Tetanus Toxoid Conjugate Vaccine for Type II Group BStreptococcusin Healthy Women

, 2000
Carol J. Baker, Lawrence C. Paoletti, Marcia A. Rench, Hilde‐Kari Guttormsen, Vincent J. Carey, Melissa E. Hickman, Dennis L. Kasper   +6 more
openalex   +1 more source

Novel Swelling‐Lytic Cell Death Triggered by Cargo‐Free Ionizable Lipid Nanoparticles

Advanced Science, EarlyView.
A cargo‐free ionizable lipid nanoparticles (ipLNP) is found to induce broad swelling‐lytic cell death across multiple cell types. Cell death may be associated with lysosome membrane destabilization, involving ROS increase, lipid peroxidation, and GSDME cleavage.
Junjun Wu, Zhennan Zhao, Hongsheng Wu, Sihuang Lin, Lin Huang, Guanjie Chen, Yi Yang, Hong Wang, Huijie Yan, Yonghui Shi, Liuyu Zhu, Guosheng Hu, Liling Zheng, Songying Ouyang   +13 more
wiley   +1 more source

Phage-resistance alters Lipid A reactogenicity: a new strategy for LPS-based conjugate vaccines against Salmonella Rissen. [PDF]

Front Immunol
Cuomo P, Medaglia C, Casillo A, Gentile A, Fruggiero C, Corsaro MM, Capparelli R.   +6 more
europepmc   +1 more source

Pneumococcal 15-valent and 20-valent conjugate vaccines for prevention of pneumococcal disease. [PDF]

Aust Prescr, 2023
europepmc   +1 more source

Conjugate pneumococcal vaccine and antibiotic-resistant Streptococcus pneumoniae : herd immunity and reduction of otitis morbidity

, 2000
Ron Dagan, Drora Fraser
openalex   +1 more source

The Efficacy of aSalmonella typhiVi Conjugate Vaccine in Two-to-Five-Year-Old Children [PDF]

, 2001
Feng Lin, Vô Anh Hó, Ha Ba Khiem, Dang Duc Trach, Phan Van Be Bay, Tran Cong Thanh, Zuzana Kossaczká, Dolores A. Bryla, Joseph Shiloach, John B. Robbins, Rachel Schneerson, Shousun C. Szu, Mai Ngoc Lanh, Steven Hunt, Loc Trinh, Jeanne B. Kaufman   +15 more
openalex   +1 more source

Rapid and Ultra‐Sensitive SARS‐CoV‐2 Subgenomic RNA Detection Using Single‐Molecule With a Large Transistor‐SiMoT Bioelectronic Platform

Advanced Electronic Materials, EarlyView.
The single‐molecule with a large transistor‐SiMoT is proposed for the detection of the subgenomic RNA of SARS‐CoV‐2, achieving a diagnostic sensitivity of 98.0% and a specificity of 87.8%. The SiMoT technology, currently at TRL‐5, is suitable for point‐of‐care settings and delivers the result to the end user in 30 min.
Eleonora Macchia, Anna Maria D'Erchia, Mariapia Caputo, Angelica Bianco, Claudia Leoni, Francesca Intranuovo, Cecilia Scandurra, Lucia Sarcina, Cinzia Di Franco, Paolo Bollella, Gaetano Scamarcio, Luisa Torsi, Graziano Pesole   +12 more
wiley   +1 more source

Expanded Recommendations for Use of Pneumococcal Conjugate Vaccines Among Adults Aged ≥50 Years: Recommendations of the Advisory Committee on Immunization Practices - United States, 2024. [PDF]

MMWR Morb Mortal Wkly Rep
Kobayashi M, Leidner AJ, Gierke R, Xing W, Accorsi E, Moro P, Kamboj M, Kuchel GA, Schechter R, Loehr J, Cohen AL.   +10 more
europepmc   +1 more source