Results 181 to 190 of about 677,036 (296)

Novel internal fixation technique for Pauwels type III neck of femur fractures using the femoral neck system in conjunction with a medial buttress plate: a case report. [PDF]

OTA Int
Sherwood D, Gunaratne R.
europepmc   +1 more source

Studies of the 17-desoxy, 17-hydroxy, and C19 androgens in conjunction with congenital adrenal hyperplasia (21-OH deficiency). [PDF]

, 1979
F Lorenzen, Songya Pang, Maria I. New, Bo Dupont, M S Pollack, Desiree Chow, L S Levine   +6 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

The ppGpp-HpaR1-gum regulatory pathway modulates exopolysaccharides production in Xanthomonas campestris pv. campestris. [PDF]

NPJ Biofilms Microbiomes
Bai K, Xu X, Yu C, Yan H, Lyu M, Jiang N, Li J, Zhang J, Wang Z, Luo L.   +9 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

The Guidance of Attentional Selectivity in Visual Search Is Always Feature-Based: Behavioral and Electrophysiological Evidence From Feature and Conjunction Search Tasks. [PDF]

Psychophysiology
Wang Z, Jimenez M, Eimer M, Grubert A.
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Interview with Prof. Dr. Jean-Marc Burgunder - 8^th European Congress on Neurorehabilitation in conjunction with the 20^th Congress of the Society for the Study of Neuroprotection and Neuroplasticity. [PDF]

J Med Life
Dobran SA, Gherman A.
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Thickness Is More Than Affective Valence: Evaluative Language Through the Lenses of Psycholinguistics. [PDF]

Cogn Sci
Cassani G, Colombo M.
europepmc   +1 more source