Results 91 to 100 of about 9,409,354 (304)

Safety of Baricitinib for the Treatment of Atopic Dermatitis in Adults Over a Median of 1.6 and up to 4.6 Years Treatment: Final Integrated Analysis of Eight Clinical Trials

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Baricitinib is a selective Janus kinase (JAK)1/JAK2 inhibitor approved in more than 70 countries for the treatment of moderate‐to‐severe atopic dermatitis (AD) in adults, and in over 30 countries for adolescents and children from age 2 years with moderate‐to‐severe AD, who are candidates for systemic therapy.
Antonio Costanzo, Antonio Torrelo, Eric L. Simpson, Marjolein De Bruin‐Weller, Diamant Thaçi, Norito Katoh, Silvia Sabatino, Andrew Buchanan, Kasia Morawska, Samuel Ogwu, Karen Denning, Jonathan I. Silverberg   +11 more
wiley   +1 more source

Testing the Sensitivity of Conjunctival Swabs from Confirmed COVID-19 Patients

Clinical Ophthalmology, 2021
Manal Hadrawi,1 Mohammad Malak,1 Faeeqah Almahmoudi,1 Ahmed Mogharbel,2 Omar Rozy,1 Somaya Hanafi,1 Batool Ali,3 Sanaa Nabeel,3 Fatimah Faqieha,4 khaled Alzahrani1 1Department of Ophthalmology, King Fahad Armed Forces Hospital, Jeddah, Saudi Arabia ...
Hadrawi M, Malak M, Almahmoudi F, Mogharbel A, Rozy O, Hanafi S, Ali B, Nabeel S, Faqieha F, Alzahrani K   +9 more
doaj  

Buccal Mucosa as Substrate for Direct Immunofluorescence Should Be Included Early in the Diagnostic Work Up of Ocular Mucous Membrane Pemphigoid

JEADV Clinical Practice, EarlyView.
ABSTRACT Background In ocular mucous membrane pemphigoid (MMP) direct immunofluorescence (DIF) represents the gold standard for definitive diagnosis. However, up to 50% of ocular MMP cases do not meet the immunopathological criteria. In addition, the risk of exacerbating conjunctival cicatrization makes ocular biopsy technically difficult to obtain ...
Andrea Gabusi, Michelangelo La Placa, Davide Bartolomeo Gissi, Federica Filippi, Camilla Loi, Cosimo Misciali, Federico Bardazzi   +6 more
wiley   +1 more source

Epidemiology and treatment options for ophthalmic complications of mucosinequiant diseases

Revista Habanera de Ciencias Médicas, 2016
Introduction: mucosinequiant diseases are those that affect skin and mucosa with blister-vesicular wounds, they are usually bilateral and are characterized by distorting the conjunctival anatomy, eyelids, lachrymal way and that universally lead to a dry ...
Yey Fano Machín
doaj  

Matrix Metalloproteinases and Glaucoma Treatment. [PDF]

, 2020
Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes that degrade extracellular matrix (ECM) components such as collagen and have important roles in multiple biological processes, including development and tissue remodeling, both in ...
Dibas, Mohammed, Robinson, Michael R, Stamer, W Daniel, Weinreb, Robert N   +3 more
core  

Organisation of Health Care During an Outbreak of Marburg Haemorrhagic Fever in the Democratic Republic of Congo, 1999. [PDF]

, 2004
Organising health care was one of the tasks of the International Scientific and Technical Committee during the 1998-1999 outbreak in Durba/Watsa, in the north-eastern province (Province Orientale), Democratic Republic of Congo.
Borchert, M, Colebunders, R, Kinuani, L, Libande, M, Mustin, J P, Muyembe-Tamfum, J J, Olinda, L A, Pirard, P, Sleurs, H, Tshioko, F, Tshomba, A   +10 more
core   +2 more sources

All‑trans‑retinoic acid modulates TGF‑β‑induced apoptosis, proliferation, migration and extracellular matrix synthesis of conjunctival fibroblasts by inhibiting PI3K/AKT signaling.

Molecular Medicine Reports, 2019
Conjunctival fiber generation is implicated in a wide spectrum of ocular diseases. Conjunctival wound healing is characterized by inflammation followed by re‑epithelialization, synthesis of new extracellular matrix (ECM), wound contraction and ...
Ling-ling Liang, Xiaomei Wang, Yajuan Zheng, Yang Liu   +3 more
semanticscholar   +1 more source

Impact of Obesity on the Structured Histopathology of Chronic Rhinosinusitis Patients

The Laryngoscope, EarlyView.
ABSTRACT Objectives Obesity is an established risk factor for asthma, which shares common inflammatory pathways with chronic rhinosinusitis (CRS). However, the link between obesity and CRS remains poorly understood. By identifying trends in the structured histopathology (SHP) of obese patients with CRS, we aim to better understand how changes in the ...
Daniel X. Ma, Sushanth Neerumalla, Ali Baird, Russell A. Whitehead, Peter Filip, Bobby A. Tajudeen, Pete S. Batra, Peter Papagiannopoulos   +7 more
wiley   +1 more source

Electrospun collagen/poly(L-lactic acid-co-ε-caprolactone) scaffolds for conjunctival tissue engineering

Experimental and Therapeutic Medicine, 2017
Conjunctival injuries are general but intractable ocular surface diseases, the sequelae of which are particularly challenging to treat. A promising therapy for conjunctival injuries is to employ biodegradable scaffolds to deliver conjunctival epithelial ...
Qinke Yao, Weijie Zhang, Yang Hu, Junzhao Chen, Chunyi Shao, Xianqun Fan, Yao Fu   +6 more
semanticscholar   +1 more source

Filomicelle‐Embedded Composite Hydrogels for Localized Gelation Within the Anterior Chamber of the Eye

Small, EarlyView.
A composite hydrogel (C‐gel) incorporating PEG‐b‐PPS filomicelles enables localized in situ gelation and sustained nanocarrier release within the anterior chamber. The filamentous structure promotes spatial confinement of multi‐arm polymer crosslinking, even upon injection into large aqueous volumes, and gradually transitions into spherical micelles ...
Hyeohn Kim, Sofia Lara Ochoa, Swagat Sharma, Asmaa A. Youssif, Benjamin R Thomson, Mark Johnson, Evan A. Scott   +6 more
wiley   +1 more source