Results 41 to 50 of about 12,424 (172)

Development of a Swine Whole Eye Transplant Ex Vivo Perfusion Protocol

Artificial Organs, EarlyView.
This study establishes the first subnormothermic machine perfusion protocol for whole eye transplants in a swine model, enabling up to 18 h of preservation with stable metabolic function, limited edema, and recovery of mydriasis. ABSTRACT Background The first human Whole Eye Transplant (WET) has sparked new hope for patients who have lost vision due to
Haïzam Oubari, Lucile Cabanel, Yanis Berkane, Ali Mojallal, Mark A. Randolph, Basak Uygun, Korkut Uygun, Curtis L. Cetrulo Jr., Alexandre G. Lellouch   +8 more
wiley   +1 more source

Congenital aniridia: European COST action ANIRIDIA‐NET guidelines for diagnosis, management and care

Acta Ophthalmologica, EarlyView.
Abstract Congenital aniridia is a rare ocular disorder affecting the majority of eye structures and can be associated with systemic manifestations. The main visible phenotypic characteristic is the partial or complete absence of the iris; however, foveal hypoplasia is a more frequent and reliable clinical sign. Other ocular comorbidities are associated
Davide Romano, Vito Romano, Alejandra Daruich, Giulio Ferrari, Matthieu Robert, Francesco Semeraro, Neil Lagali, Dominique Bremond‐Gignac, the ANIRIDIA‐NET Clinical Guidelines Working Group, Miriam Barbany, Claus Cursiefen, Stefano Ferrari, Francisco Figueiredo, Christina Grupcheva, Jesper Hjortdal, Elke Kreps, Erlend Landsend, Laura Mauring, Hilde Pedersen, Nora Szentmáry, Bogumil Wowra, the Aniridia‐Europa and Geniris Working Group, Sophie Valleix, Juan Álvarez de Toledo, James Lauderdale, Tor Paaske Utheim, Paolo Rama   +26 more
wiley   +1 more source

Blindness and prognostic factors after trabeculectomy with mitomycin C in patients with open‐angle glaucoma with long‐term follow‐up

Acta Ophthalmologica, EarlyView.
Abstract Purpose To determine the long‐term blindness rate and related prognostic factors in eyes with open‐angle glaucoma after trabeculectomy using adjunctive mitomycin C (MMC). Methods The retrospective cohort study included 714 eyes from 714 patients with open angle glaucoma who underwent trabeculectomy using MMC.
Masato Matsuo, Akira Sawada, Taishi Miyase, Masayuki Inuzuka, Masaomi Kubota, Tetsuya Yamamoto   +5 more
wiley   +1 more source

Terapia auxiliar com o tranilast pré-operatório na cirurgia do pterígio primário com um ano de seguimento [PDF]

, 2015
Purpose: To determine the efficacy of tranilast as an adjunctive therapy in conjunctival autograft. Methods: Twenty-nine patients were randomly allocated to the Tranilast Group (n=15) or the Control Group (n=14).
Almeida Júnior, Gildásio Castello de, Alves, Milton Ruiz, Arakawa, Luciano, Azoubel, Reinaldo, Cury, Patrícia Maluf, Lima Filho, Acácio Alves de Souza, Santi Neto, Dalísio de, Sousa, Sidney Julio de Faria e   +7 more
core   +3 more sources

Outcome parameters in studies investigating dry eye disease: A systematic literature review

Acta Ophthalmologica, EarlyView.
Abstract The development of effective therapeutics for dry eye disease (DED) is challenging due to its complex pathophysiology, heterogeneous patient presentation and the significant failure rate of previous clinical development programs. This underlines the importance of the selection of appropriate endpoints for clinical trials.
Viktoria Pai, Doreen Schmidl, Liudmyla Petric, Patrick Janku, Theresa Lindner, Ulrich Graf, Jacqueline Chua, Leopold Schmetterer, Gerhard Garhöfer   +8 more
wiley   +1 more source

Amniotic membrane graft versus conjunctival autograft for the management of primary pterygium

Al-Azhar Assiut Medical Journal, 2018
Aim To compare amniotic membrane graft versus conjunctival autograft for the management of primary pterygium. Design A prospective, randomized study. Patients and methods Fifty eyes of 50 patients with primary pterygium were prospectively included in ...
Ashraf M Gad Elkareem, Asaad Nooreldin
doaj   +1 more source

Aniridia‐associated keratopathy: Clinical and molecular mechanisms of disease progression and emerging therapeutic targets

Acta Ophthalmologica, EarlyView.
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry, S. Suiwal, M. Amini, F. N. Fries, A. Náray, L. Latta, Z. Li, S. Li, S. Liu, S. L. Hsu, S. Kundu, G. Tóth, S. Trusen, J. Zimmermann, B. Seitz, B. Käsmann‐Kellner, Z. Hoxha, A. Langenbucher, O. Stachs, M. Cortón‐Perez, K. Tory, A. Csorba, Z. Z. Nagy, M. C. Acosta, J. Gallar, M. Csidey, E. Maka, T. Stachon   +27 more
wiley   +1 more source

Sutureless and glue free conjunctival auto grafting after pterygium excision

IMC Journal of Medical Science, 2016
Background and objectives: Suture or glue has been used to secure the conjunctival auto graft after excision of the pterygium. Recently, auto grafting using patient’s own blood as a bioadhesive to secure the graft in position has been described by ...
MK Goswami, Md Asaduzzaman
doaj  

Concomitant use of conjunctival tissue graft from the pterygium itself without rotation in pterygium surgery: A full circle in conjunctival autografting

Indian Journal of Ophthalmology, 2018
Purpose: The aim of this study is to describe a modified technique of using conjunctival tissue from the pterygium itself without any rotation of graft for the primary pterygium in eyes with glaucoma filtering bleb, glaucoma suspects, and in primary ...
Shreesha Kumar Kodavoor, Nitin Narendra Tiwari, Dandapani Ramamurthy   +2 more
doaj   +1 more source

Enxerto de látex natural na cicatrização de esclerectomias lamelar e penetrante em coelhos [PDF]

, 2009
The objective of study was to investigate the effects of natural latex with 0.1% of polylysine on lamellar and penetrating scleroctomies in rabbits. Two groups of twelve rabbits each (lamellar GI and penetrating GII) were studied.
COUTINHO-NETTO, Joaquim, LAUS, José Luiz, LUVIZOTTO, Maria Cecília Rui, PAULA, Meiby Carneiro de, TALIERI, Ivia Carmem   +4 more
core   +3 more sources