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Allergic Conjunctivitis: An Update

Handbook of Experimental Pharmacology, 2021
Conjunctivitis is a frequent disease of the eye with the typical clinical sign being the "red eye" and comprises a very heterogeneous group with different causes. In general, infectious conjunctivitis must be strictly differentiated from non-infectious conjunctivitis.
A. Mueller
openaire   +4 more sources

Chemokines in allergic conjunctivitis

Current Opinion in Allergy & Clinical Immunology, 2020
Purpose of reviewChemokines are a large group of low molecular weight cytokines that attract and activate leukocytes throughout the body and therefore have a key role in the framework of late-phase allergic responses. The purpose of this article is to provide an overview of the main chemokines involved in allergic conjunctivitis, their primary ...
Nir, Erdinest   +2 more
openaire   +3 more sources

Clinically Relevant Activity of the Novel RASP Inhibitor Reproxalap in Allergic Conjunctivitis: The Phase 3 ALLEVIATE Trial.

American journal of ophthalmology-glaucoma, 2021
PURPOSE To assess the post-acute activity and clinical utility of reproxalap, a novel reactive aldehyde species (RASP) inhibitor, versus vehicle in patients with seasonal allergic conjunctivitis. DESIGN Parallel-group, double-masked, randomized Phase 3
D. Clark   +5 more
semanticscholar   +1 more source

Allergic Conjunctivitis

Immunology and Allergy Clinics of North America, 2008
Allergic conjunctivitis is common, especially during the allergy season. Consultation with the allergist to perform skin tests or in vitro tests may be useful and confirmatory in the diagnosis of ocular allergy. If treatment is necessary, antihistamines, mast cell stabilizers, and nonsteroidal anti-inflammatory drugs are safe and reasonably effective ...
Leonard, Bielory   +1 more
openaire   +2 more sources

Seasonal allergic conjunctivitis

Drugs of Today, 1998
Seasonal allergic conjunctivitis is rarely associated with permanent vision impairment; however, it is a relatively common condition that may compromise the quality of life of patients with this diagnosis. In extreme cases daily activities, including work, may be compromised.
J, Joss, T, Craig
openaire   +2 more sources

Allergic Conjunctivitis

Ophthalmology, 2023
Allergic conjunctivitis is the most common manifestation of conjunctivitis, affecting up to 40% of the population, mostly children and young adults. Among the risk factors there are air pollution, southern latitude and coexisting allergy. The disease develops when IgE-class antibodies are activated by an allergen and later Th2-dependent humoral ...
Karolina Ciepiaszuk   +3 more
openaire   +1 more source

Chronic allergic conjunctivitis

Ocular Immunology and Inflammation, 1993
Chronic allergic conjunctivitis (CAC) or perennial allergic conjunctivitis (PAC) is the most frequent form of allergy of the conjunctiva that is encountered in Northern Europe, particularly in city areas. Itching, redness of the mucosa, swelling of the lids and tearing are the main symptoms.
E, Blochmichel   +2 more
openaire   +2 more sources

Allergen Immunotherapy: The Evidence Supporting the Efficacy and Safety of Subcutaneous Immunotherapy and Sublingual Forms of Immunotherapy for Allergic Rhinitis/Conjunctivitis and Asthma.

Journal of Allergy and Clinical Immunology: In Practice
Allergen immunotherapy is a recognized key therapeutic modality for the treatment of allergic respiratory disease - definitive studies have provided evidence-based data to demonstrate its effectiveness in allergic rhinitis and asthma due to the ...
P. Creticos   +4 more
semanticscholar   +1 more source

Tofacitinib suppresses mast cell degranulation and attenuates experimental allergic conjunctivitis.

International Immunopharmacology, 2020
BACKGROUND Allergic conjunctivitis (AC), a common eye inflammation that affects patients' health and quality of life, is still a therapeutic challenge for ophthalmologists.
Yingqi Li   +8 more
semanticscholar   +1 more source

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