Results 61 to 70 of about 12,572 (253)

Mapping Genetic Regulation of Transcription to Identify Functional Variants and Genes Associated with Pancreatic Cancer Risk

Advanced Science, EarlyView.
Integration of a pancreatic eQTL map with a GWAS meta‐analysis identifies 82 putative functional variants and 15 genes. The association between rs11102484 and pancreatic cancer risk is observed in a total of 5699 cases and 8467 controls. The G allele of rs11102484 weakens ZNF263 binding and the silencer‐promoter interaction, thereby increasing ST7L ...
Xiaoyang Wang, Hui Geng, Zhengyan Yao, Yuan Jiang, Can Chen, Zequn Lu, Shuangshuang Tian, Ming Zhang, Ruiyan Liu, Chenxi Feng, Bin Li, Xiaoping Miao, Jianbo Tian, Shaokai Zhang, Ying Zhu   +14 more
wiley   +1 more source

Celebrating lessons and carrying on legacies from Christine M. Porter

Journal of Agriculture, Food Systems, and Community Development
First paragraph: This compilation of vignettes emerged from an invitation to share and celebrate food justice and other lessons and legacies con­nected with Christine M. Porter, as she prepared to walk on in 2024.
Patti Provance, Megan Gregory, Lacey Gaechter, Alyssa Duba, Shannon Conk, Ben Cousineau, Lindsey Lunsford, Erica Hall, Derek Smith, Katherine McKinney, Denyse Ute, Sarah Konrad, Rachael Budowle   +12 more
doaj   +3 more sources

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

Advanced Science, EarlyView.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang, Xi Dai, Shuaihu Li, Yingxue Chen, Yaxin Yu, Lin Wang, Kun Liu, Shuhan Lyu, Chongyang Li, Yihua Sun, Fei Li   +10 more
wiley   +1 more source

Passivation‐Induced Species Dynamics and Microstructural Evolution in Solid‐State Lithium–Sulfur Cathodes

Advanced Science, EarlyView.
The formation of insulating Li2S during discharge in solid‐state lithium–sulfur batteries passivate reaction sites and limits sulfur utilization. In this work, a microstructure‐resolved modeling framework coupling transport and reaction kinetics is developed to predict charge–discharge behavior and reveal particle‐scale species evolution and incomplete
Arpan K. Sharma, Bairav S. Vishnugopi, Elif Pınar Alsaç, Matthew T. McDowell, Partha P. Mukherjee   +4 more
wiley   +1 more source

Âşık Ömer Divanı’na Katkılar VII

Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2020
Âşık Ömer 17. yüzyılda yaşamış önemli bir halk şairidir. Şiirleri incelendiğinde onun sadece halk şiiri tarzında değil, aynı zamanda divan şairleriyle boy ölçüşecek seviyede aruzla şiirler yazdığı anlaşılmaktadır.
Orhan Yavuz, Fatih Numan Küçükballı
doaj  

Congruence amalgamation of lattices

, 2005
J. Tuma proved an interesting "congruence amalgamation" result. We are generalizing and providing an alternate proof for it. We then provide applications of this result: --A.P.
Grätzer, George, Lakser, Harry, Wehrung, Friedrich   +2 more
core  

Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment

Advanced Science, EarlyView.
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun, Haili Hu, Long Chen, Yuan Gao, Peng Sun, Liming Chen   +5 more
wiley   +1 more source

Biochemical Composition and Medicinal Properties of Inonotus obliquus Pil.

Техника и технология пищевых производств
Birch chaga is a popular functional component. This fungus is rich in chemical and biologically active substances, but the composition is so complex that their extraction remains a challenge.
Burenkov Sergey, Zaushintsena Alexandra
doaj   +1 more source

DNA Replication Errors Drive Genome‐Wide Small Inverted Triplication Dynamics

Advanced Science, EarlyView.
This study provides insight into the dynamic equilibrium mechanism of a novel structural variant, small inverted triplication (SIT), which is generated by misalignment of the 3’ flap generated under DNA replication stress with palindromic sequence. Alternatively, the end sequence may fold back on itself to form an inverted fragment.
Yi Lei, Yu Zhou, Haitao Sun, Hang Yuan, Xinyu Pei, Jessica D. Hess, Yao Yan, Zunsong Hu, Mian Zhou, Zhaohui Gu, Li Zheng, Xiwei Wu, Binghui Shen   +12 more
wiley   +1 more source

Spartan Daily, October 29, 1942 [PDF]

, 1941
Volume 31, Issue 21https://scholarworks.sjsu.edu/spartandaily/3501/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core   +2 more sources