Results 201 to 210 of about 1,339 (249)

Attempts at active protection of Inonotus obliquus by inoculating birches with its mycelium [PDF]

core   +2 more sources

A Framework for Subgroup Dynamics Through the System Dynamics Lens: An Integrative Review of the Attribute and the Network Views

Journal of Organizational Behavior, EarlyView.
ABSTRACT Subgroups are dynamic entities evolving constantly in response to changing contexts and time. Although scholars from both the attribute and the network views have acknowledged that subgroups are inherently complex and fluid, research in these traditions has remained bifurcated, with limited efforts to integrate the two perspectives to more ...
Jinhee Moon, Chunghyun Oh, Chou‐Yu Tsai, Semin Park   +3 more
wiley   +1 more source

I Can't Split Myself in Two (or Five): Job Crafting in Highly Demanding and Interdependent Work Environments

Journal of Organizational Behavior, EarlyView.
ABSTRACT Employees in highly demanding, interdependent work environments face a dilemma: while avoidance‐focused job crafting can preserve their own well‐being, these self‐initiated changes to their jobs could negatively affect coworkers. Drawing on qualitative interviews with 81 employees concurrently working for multiple agile teams in a European ...
Helene Tenzer, Martin Hoegl, Maria Tims, Philip Yang, Steffen Wütz   +4 more
wiley   +1 more source

Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to
Msimisi Ndzinisa, Birhanetensay Masresha Altaye, Yuh‐Pyng Sher   +2 more
wiley   +1 more source

How Do Older Patients With Advanced Kidney Disease, and Their Family Members, Understand Kidney Function and Failure? A Qualitative Study

Snead CM, Kimmitt RA, Caskey FJ, Darling J, Rooshenas L, Coast J, Morton RL, Selman LE, Hole B.   +8 more
europepmc   +1 more source

Laurels or Thorns of Trust? How Embeddedness Moderates the Exchange‐Satisfaction Relationship in Franchising

Managerial and Decision Economics, EarlyView.
ABSTRACT Exchanges in franchise systems are embedded in the level of trust that exists in franchisee–franchisor relationships. Although trust is essential in business relationships, it can unfold a negative side effect on the appreciation of exchange in these relationships as hidden costs of trust.
Matthias Glaser, Josef Windsperger, Evelien Croonen   +2 more
wiley   +1 more source

Modulation of the Stress Granule Component Carhsp1 Mitigates Disease‐Associated Deficits in Spinocerebellar Ataxia Type 3 Mouse Models

Movement Disorders, EarlyView.
Abstract Background Spinocerebellar ataxia type 3 (SCA3) is a polyglutamine (polyQ) neurogenerative disorder that results from CAG trinucleotide repeat expansions in the ATXN3 gene, leading to toxic protein aggregate formation and cellular pathway dysfunction.
Tiago Moreira‐Gomes, Adriana Marcelo, Ana Teresa Rajado, Rafael G. Costa, Ricardo Afonso‐Reis, Cristiana R. Madeira, Inês T. Afonso, David V.C. Brito, Adriana A. Vaz, Clévio Nóbrega   +9 more
wiley   +1 more source

Respiratory Syncytial Virus (RSV): A Comprehensive Overview From Basic Biology to Clinical Prevention and Control

Medicinal Research Reviews, EarlyView.
ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi, Xiya Huang, Chunjun Ye, Yishan Lu, Yanyan Liu, Yuquan Wei, Xiawei Wei   +6 more
wiley   +1 more source

Smart Integration of Structural Biology and Medicinal Chemistry to Unlock Target‐Driven Drug Discovery

Medicinal Research Reviews, EarlyView.
ABSTRACT To enhance drug discovery efforts, medicinal chemists should evaluate, filter, and utilize relevant structural information about target proteins. Acquiring and interpreting protein structures is crucial for elucidating ligand‐receptor interactions and addressing ADME‐related considerations, making it an essential aspect of medicinal chemistry.
Matteo Rossi Sebastiano, Giulia Apprato, Serena Francisco, Giuseppe Ermondi, Giulia Caron   +4 more
wiley   +1 more source

Navigating the Rapids: How Non‐Governmental Organization Managers Develop Strategic Adaptation to Repressive Political Environments

Public Administration and Development, EarlyView.
ABSTRACT This article explores the management adaptation strategies non‐governmental organizations (NGOs) managers employ in order to operate in repressive political environments. It answers the question: how do NGO managers initiate, manage and sustain internal change when the political/regulatory environment changes?
Charles Kaye‐Essien, Shahjahan Bhuiyan, Ghadeer Ali   +2 more
wiley   +1 more source