Results 61 to 70 of about 87,170,517 (282)

A closer look at the relationships between aspects of connectedness and flourishing

Frontiers in Psychology, 2023
Everyone strives for personal happiness or well-being. Flourishing is a broader concept of well-being. To better understand which factors are associated to people’s flourishing, we took a closer look at the relationships of flourishing with three aspects
Martina Rahe, Petra Jansen
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

The green care code: How nature connectedness and simple activities help explain pro‐nature conservation behaviours

, 2020
The biodiversity crisis demands greater engagement in pro‐nature conservation behaviours. Research has examined factors which account for general pro‐environmental behaviour; that is, behaviour geared to minimizing one's impact on the environment. Yet, a
Holli‐Anne Passmore, Richardson, Miles, Passmore, Holli‐Anne, Ryan Lumber, Lumber, Ryan, Lea Barbett, Thomas, Rory, Miles Richardson, barbett, lea, Alex Hunt, Rory Thomas, Hunt, Alex   +11 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Escala de conexão com a natureza: evidências psicométricas no contexto brasileiro

Estudos de Psicologia (Campinas)
Este artigo objetivou reunir evidências de validade e precisão da Connectedness to Nature Scale no contexto brasileiro. Dois estudos foram realizados.
Viviany Silva PESSOA, Valdiney Veloso GOUVEIA, Ana Karla Silva SOARES, Roosevelt VILAR, Leogildo Alves FREIRES   +4 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Situation Networks: The emotions and activities that are central to nature-connectedness experiences [PDF]

Many of the psychological phenomena that are relevant to the environmental crises facing the globe are determined by a complex set of interrelated constructs—that is, they are determined by a network of factors.
Richardson, Miles, Aviste, Rosemary, Lengieza, Michael L., Lengieza, M. L., Aviste, R., Richardson, M.   +5 more
core   +1 more source

Exploring the Construct of Relational Values: An Empirical Approach

Frontiers in Psychology, 2020
In recent environmental research, relational values (RVs) have emerged as a new group of values to explain environmental behavior. Although this new concept is attracting attention, empirical studies on the subject are still rare.
Matthias Winfried Kleespies, Paul Wilhelm Dierkes   +1 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source