Results 181 to 190 of about 5,844,415 (324)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Going straight in a sacred landscape: the Great Hopewell Road

Studies in Digital Heritage
The Hopewell culture built a series of geometric earthworks, among which the Newark Earthworks stand out as the most complex.  It has long been suspected that a ceremonial, double-walled straight road connected Newark with the Hopewell Heartland ...
Giulio Magli, Brad Lepper
doaj  

The Influence of Deep Space and the Stars on Emotions. [PDF]

Int J Psychol
Martens JP, Prokopetz M, Tomlinson K.
europepmc   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Erratum for “Strain Distribution of Dowel-Type Connections Reinforced with Self-Tapping Screws” by Cong Zhang, Richard Harris, and Wen-Shao Chang [PDF]

, 2020
Cong Zhang, Richard Harris, Wen‐Shao Chang   +2 more
openalex   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Development of a novel high-performance portable barrier based on full-scale field tests and simulation optimization. [PDF]

Sci Rep
Wang F, Xiang G, Cheng Q, Zhang Y, Fang X, Xu X.   +5 more
europepmc   +1 more source

Projective and affine transformations of a complex symmetric connection [PDF]

, 1994
Novica Blažić, Neda Bokan
openalex   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini, Paolo Preziosa, Paola Valsasina, Damiano Mistri, Monica Margoni, Federica Esposito, Massimo Filippi, Maria A. Rocca   +7 more
wiley   +1 more source

Coaching effectiveness in competitive youth contact sports and martial arts: athletes' and coaches' perceptions. [PDF]

Front Psychol
Müjdeci İ, Kılıç K, Bulut A, Kuru H.   +3 more
europepmc   +1 more source