Results 41 to 50 of about 295,579 (265)

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

On the Problem of Undirected st-connectivity

CoRR, 2022
In this paper, we discuss an algorithm for the problem of undirected st-connectivity that is deterministic and log-space, namely that of Reingold within his 2008 paper "Undirected Connectivity in Log-Space". We further present a separate proof by Rozenman and Vadhan of $\text{USTCONN} \in L$ and discuss its similarity with Reingold's proof.
Shilun Li, Alex Lee
openaire   +2 more sources

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

On the complexity of the vector connectivity problem

Theoretical Computer Science, 2015
We study a relaxation of the Vector Domination problem called Vector Connectivity (VecCon). Given a graph $G$ with a requirement $r(v)$ for each vertex $v$, VecCon asks for a minimum cardinality set $S$ of vertices such that every vertex $v\in V\setminus S$ is connected to $S$ via $r(v)$ disjoint paths. In the paper introducing the problem, Boros et al.
Cicalese, Ferdinando, Milanič, Martin, RIZZI, ROMEO   +2 more
openaire   +5 more sources

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Tightness and Material Aspects of Bolted Flange Connections With Gaskets of Nonlinear Properties Exposed to Variable Loads

Archives of Metallurgy and Materials, 2016
The paper presents the problems regarding bolted flange connections with gaskets used in chemical, petrochemical and energy industry. The aim of the research is to present state of knowledge regarding pipelines and apparatus in industrial installations ...
Walczak R., Pawlicki J., Zagórski A.
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

The mediating role of the connection with nature in the relationship between behavioral problems and emotion regulation in early childhood

Frontiers in Psychology
IntroductionThis study aims to investigate the mediating role of connection to nature in the relationship between behavioral problems and emotion regulation in preschool children.MethodsA cross-sectional research design was used to collect data from a ...
Melike Aykut, H. Gözde Ertürk Kara
doaj   +1 more source

Edge-connectivity augmentation problems

Journal of Computer and System Sciences, 1987
We give a characterization on the minimum number of edges to be added so as to k-edge-connect a graph. We also show that such a minimum edge set can be determined in \({\mathcal O}(kL| V|^ 4(k| V| +| E|))\) time for any graph \(G=(V,E)\) and any fixed \(k\geq 2\), where \(L=\min \{k,| V| \}\).
Toshimasa Watanabe, Akira Nakamura
openaire   +2 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source