Results 221 to 230 of about 1,969,271 (290)

Gut Microbiota‐Derived Indole‐3‐Propionic Acid Alleviates Diabetic Osteoporosis Through Nrf2‐Mediated Ferroptosis Suppression

Advanced Science, EarlyView.
Diabetes‐associated dysbiosis is accompanied by reduced Clostridium abundance, impaired microbial tryptophan metabolism, and lower circulating indole‐3‐propionic acid (IPA). Exogenous IPA improves trabecular microarchitecture and bone formation and restores Nrf2‐associated antioxidant signaling in bone marrow mesenchymal stem cells, limiting iron ...
Jinwu Bai, Qinyong You, Gao Si, Daole Hu, Ao Sun, Shilong Su, Ruideng Wang, Jixing Fan, Shan Gao, Tengjiao Zhu, Chun‐Li Song, Fang Zhou, Yang Lv   +12 more
wiley   +1 more source

A Regenerative Breakthrough in the Management of a Cystic Lesion Using a Novel Combination of Eggshell-Derived Nanohydroxyapatite (EnHA) and Concentrated Growth Factor: A Case Report. [PDF]

Cureus
Gujral A, Sane V, Joshi AS, Nair VS, Thorat R, Sane R.   +5 more
europepmc   +1 more source

Multifunctional Nanovaccine‐Radiotherapy Synergy Drives Anti‐Tumor Immunity via Multi‐Cascade Cell Death for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
Machine‐learning‐driven transcriptomic analysis identifies FSTL3 as a key tumor‐microenvironment regulator in desmoplastic pancreatic adenocarcinoma. A cRGD‐modified liposome co‐loading gemcitabine and siFSTL3 serves as an irradiation‐triggered in situ nanovaccine. It synergizes with radiotherapy to induce ferroptosis and immunogenic cell death through
Chengyi Huang, Yushu Han, Xiang Liu, Chuanhao Wang, Xiaofei Zhu, Di Chen, Yangyang Gong, Liang Chen, Wenjuan Chen, Zhenyuan Miao, Bufu Tang, Huojun Zhang   +11 more
wiley   +1 more source

Posterior Maxillary Implant Rehabilitation Using Staged Ridge Preservation and Soft-Tissue Augmentation: A 2-Year Case Report. [PDF]

Case Rep Dent
Daouahi N, Gassara Y, Slim A, Abdellatif C.   +3 more
europepmc   +1 more source

Sequential Regulation of Neurovascular Bone Regeneration in Large Bone Defects Using Black Phosphorus‐Europium Nanosheet Integrated TPMS Biomimetic Scaffold with Photo‐Controlled Ion Release

Advanced Science, EarlyView.
TPBE scaffolds, in conjunction with mild photothermal effects, effectively activate the PI3K/Akt signaling cascade, thereby promoting early neuronal differentiation and neurite growth. Short‐term (12 W) in vivo implantation studies revealed no significant pathological damage to major organs, providing preliminary evidence of the material's excellent ...
Bingqian Wang, Yuping Zhang, Xiaoning Su, Ning Liu, Hui Zeng, Bo Yang, Yang Xue, Fang Guo, Changkui Liu   +8 more
wiley   +1 more source

A novel growth factor bioavailability-enhanced allograft for use in craniomaxillofacial bone regeneration. [PDF]

Front Bioeng Biotechnol
Peel SAF, Terryberry J, Naseri S, Orth CF.   +3 more
europepmc   +1 more source

Engineered Transformer Base Editor with Enhanced Editing Efficiency

Advanced Science, EarlyView.
A highly efficient transformer base editor system achieves robust genomic editing in a humanized mouse model. This work establishes a versatile and translatable platform, opening new avenues for precision gene therapy. ABSTRACT Canonical cytosine base editors (CBEs) achieve precise C‐to‐T conversions without inducing DNA double‐strand breaks (DSBs ...
Bowen Chen, Letong Liang, Rui Xu, Tianyi Wang, Hongyan Chen, Daru Lu   +5 more
wiley   +1 more source

Transcatheter Electrosurgical Aortic Septotomy Across the Spectrum of Type B Aortic Dissection: Feasibility, Technical Lessons, and Bailout Strategies. [PDF]

EJVES Vasc Forum
Liu MY, Chi NH, Chen YS, Huang SC, Wu IH.   +4 more
europepmc   +1 more source

Recurrent Dystrophic Calcification and Squamous Cell Carcinoma in a Cultured Keratinocyte Scar 35 Years After a 60% Total Body Surface Area Flame Burn. [PDF]

Plast Reconstr Surg Glob Open
Carnio A, Costa AL, Vindigni V, Bassetto F.   +3 more
europepmc   +1 more source