Results 91 to 100 of about 64,126 (335)
Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice
Advanced Science, EarlyView.Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia +29 more
wiley +1 more source
The connectome spectrum as a canonical basis for a sparse representation of fast brain activity
NeuroImage, 2021 The functional organization of neural processes is constrained by the brain's intrinsic structural connectivity, i.e., the connectome. Here, we explore how structural connectivity can improve the representation of brain activity signals and their ...
Joan Rué-Queralt +7 more
doaj
Annual Review of Statistics and Its Application, 2020 The data science of networks is a rapidly developing field with myriad applications. In neuroscience, the brain is commonly modeled as a connectome, a network of nodes connected by edges. While there have been thousands of papers on connectomics, the statistics of networks remains limited and poorly understood.
Jaewon Chung +8 more
openaire +3 more sources
Advanced Intelligent Systems, EarlyView.This study, utilizing two large‐cohort datasets, employs interpretable neural networks. It demonstrates that incorporating brain morphology and functional and structural networks enhances predictive accuracy for general psychopathology and its dimensions.
Jing Xia, Nanguang Chen, Anqi Qiu
wiley +1 more source
Functional connectome of human cerebellum
NeuroImage, 2022 Background Neural connectome theory has been widely used in system neuroscience, and prompted our comprehension for the topological organizations of human cerebral cortex.
Zhiyi Chen +5 more
doaj
Local connectome phenotypes predict social, health, and cognitive factors [PDF]
Network Neuroscience, 2018 The unique architecture of the human connectome is defined initially by genetics and subsequently sculpted over time with experience. Thus, similarities in predisposition and experience that lead to similarities in social, biological, and cognitive ...
Michael A. Powell +4 more
doaj +1 more source
Focused Proofreading: Efficiently Extracting Connectomes from Segmented EM Images [PDF]
, 2014 Identifying complex neural circuitry from electron microscopic (EM) images may help unlock the mysteries of the brain. However, identifying this circuitry requires time-consuming, manual tracing (proofreading) due to the size and intricacy of these image
Plaza, Stephen M.
core
The fly connectome reveals a path to the effectome
NatureA goal of neuroscience is to obtain a causal model of the nervous system. The recently reported whole-brain fly connectome1–3 specifies the synaptic paths by which neurons can affect each other, but not how strongly they do affect each other in vivo.
Dean A. Pospisil +12 more
semanticscholar +1 more source
Cerebral Small Vessel Disease in Older Adults With Olfactory Dysfunction
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Poor vascular health has been associated with age‐related declines in sensory functions, including olfaction. The current study was designed to test the hypothesis that cerebral small vessel disease underlies poor olfactory function due to structural declines in brain regions that support olfaction.
Mark A. Eckert +3 more
wiley +1 more source
Contracted functional connectivity profiles in autism
Molecular AutismObjective Autism spectrum disorder (ASD) is a neurodevelopmental condition that is associated with atypical brain network organization, with prior work suggesting differential connectivity alterations with respect to functional connection length.
Clara F. Weber +13 more
doaj +1 more source