Results 101 to 110 of about 52,544 (272)
Brain Pathology, EarlyView.Default mode network (DMN) consists, in part, of the frontal (FC), precuneus (PreC), and posterior cingulate cortex (PCC), which plays a critical role in episodic memory and retrieval of autobiographical memories, displays spatiotemporal differences in the onset of amyloid and hypometabolism that reflects tau neurodegeneration and loss of connectivity ...
Sylvia E. Perez +8 more
wiley +1 more source
Focused Proofreading: Efficiently Extracting Connectomes from Segmented EM Images [PDF]
, 2014 Identifying complex neural circuitry from electron microscopic (EM) images may help unlock the mysteries of the brain. However, identifying this circuitry requires time-consuming, manual tracing (proofreading) due to the size and intricacy of these image
Plaza, Stephen M.
core
Applications of MRI Connectomics
, 2021 Structural and functional brain connectomics are considered a basis for an individual's behavior and cognition. Therefore, deviations from typical connectivity patterns may indicate disease processes, and can potentially serve as disease biomarkers. To date, the direct clinical application of brain connectivity measures for diagnostics or treatment is ...
Jessica S. Damoiseaux +3 more
openaire +4 more sources
Experimental Parkinsonism induced by tetanus toxin injected into basal ganglia
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Local inhibitory circuits and long‐range inhibitory projections within the interconnected basal ganglia nuclei are critical for control of voluntary movement and pathophysiology of different extrapyramidal movement disorders.
Patrik Meglić +6 more
wiley +1 more source
A reappraisal of the default mode and frontoparietal networks in the common marmoset brain
Frontiers in NeuroimagingIn recent years the common marmoset homolog of the human default mode network (DMN) has been a hot topic of discussion in the marmoset research field. Previously, the posterior cingulate cortex regions (PGM, A19M) and posterior parietal cortex regions ...
Takuto Okuno +2 more
doaj +1 more source
Atypical functional connectome hierarchy in autism
Nature Communications, 2019 Autism spectrum disorder (ASD) is associated with symptoms ranging from sensory hypersensitivity to social difficulties. Here, the authors provide evidence of atypical connectivity transitions between sensory and higher-order cortical areas in people ...
Seok-Jun Hong +10 more
doaj +1 more source
Developmental Medicine &Child Neurology, EarlyView.The pathophysiology of D/EE‐SWAS has traditionally been conceptualized as a cause–effect continuum wherein genetic and environmental factors influence brain morphology, subsequently inducing electrical abnormalities during sleep, resulting in cognitive impairment.
Luca Andreoli +2 more
wiley +1 more source
Epilepsia, EarlyView.Abstract In drug‐resistant epilepsy, magnetic resonance imaging (MRI) plays a central role in detecting lesions as it offers unmatched spatial resolution and whole‐brain coverage. In addition, the last decade has witnessed continued developments in MRI‐based computer‐aided machine‐learning techniques for improved diagnosis and prognosis. In this review,
Andrea Bernasconi +2 more
wiley +1 more source
Epilepsia, EarlyView.Abstract Objective Patients with tuberous sclerosis complex (TSC)‐related epilepsy often have drug‐refractory epilepsy and numerous potential epileptogenic tubers. Current clinical methods target tubers for resection, but prediction of resulting seizure relief is difficult.
Kara B. Miecznikowski +6 more
wiley +1 more source
Schizophrenia, neuroimaging and connectomics
NeuroImage, 2012 Schizophrenia is frequently characterized as a disorder of brain connectivity. Neuroimaging has played a central role in supporting this view, with nearly two decades of research providing abundant evidence of structural and functional connectivity abnormalities in the disorder.
Alex Fornito +4 more
openaire +3 more sources