Results 111 to 120 of about 64,126 (335)
Molecular BrainMapping the neural circuit of a specific neuronal subclass is central to understanding the working mechanism of the brain. Currently, numerous types of transgenic mice expressing Cre recombinase have been engineered and widely used in neuroscience.
Hu You +5 more
doaj +1 more source
A computational model of shared fine-scale structure in the human connectome. [PDF]
PLoS Computational Biology, 2018 Variation in cortical connectivity profiles is typically modeled as having a coarse spatial scale parcellated into interconnected brain areas. We created a high-dimensional common model of the human connectome to search for fine-scale structure that is ...
J Swaroop Guntupalli +2 more
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The connectome of the adult Drosophila mushroom body provides insights into function
eLife, 2020 Making inferences about the computations performed by neuronal circuits from synapse-level connectivity maps is an emerging opportunity in neuroscience.
Feng Li +24 more
semanticscholar +1 more source
A Convergent Pathway for Stimulation‐Induced Dyskinesia Following Deep Brain Stimulation
Movement Disorders, EarlyView.Abstract Background Stimulation‐induced dyskinesias (SID) from deep brain stimulation (DBS) of the subthalamic nucleus (STN) and globus pallidus internus (GPi) are uncommon; however, they are increasingly recognized. Once considered transient and indicative of effective neuromodulation, SID are now seen as potential therapy‐limiting side effects, akin ...
Joshua K. Wong +4 more
wiley +1 more source
Distributed harmonic patterns of structure-function dependence orchestrate human consciousness
Communications Biology, 2023 Connectome harmonic decomposition analysis reveals how neuromodulation and the network architecture of the human connectome jointly shape consciousness and distributed functional activation across scales.
Andrea I. Luppi +18 more
doaj +1 more source
Imaging Genetic Based Mediation Analysis for Human Cognition
Frontiers in Neuroscience, 2022 The brain connectome maps the structural and functional connectivity that forms an important neurobiological basis for the analysis of human cognitive traits while the genetic predisposition and our cognition ability are frequently found in close ...
Tingan Chen +3 more
doaj +1 more source
Evaluating 35 Methods to Generate Structural Connectomes Using Pairwise Classification
, 2017 There is no consensus on how to construct structural brain networks from diffusion MRI. How variations in pre-processing steps affect network reliability and its ability to distinguish subjects remains opaque.
A Daducci +13 more
core +1 more source
The organisation of the elderly connectome [PDF]
NeuroImage, 2015 Investigations of the human connectome have elucidated core features of adult structural networks, particularly the crucial role of hub-regions. However, little is known regarding network organisation of the healthy elderly connectome, a crucial prelude to the systematic study of neurodegenerative disorders. Here, whole-brain probabilistic tractography
Perry, A +7 more
openaire +4 more sources
Movement Disorders, EarlyView.Abstract Traditionally, clinical trials of putative disease‐modifying therapies in Parkinson's disease have enrolled untreated patients at the earliest clinical stages of their disease. Due to a number of challenges inherent with this approach, there has been a recent move to a different study design, enrolling patients who are already taking “stable ...
M. Maral Mouradian +2 more
wiley +1 more source
Connectome Classification: Statistical Connectomics for Analysis of Connectome Data
, 2014 Slides for talk I gave at Duke University on April 2011.
openaire +2 more sources