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Advanced neuroinformatics tools are required for methods of connectome mapping, analysis and visualization. The inherent multi-modality of connectome datasets poses new challenges for data organization, integration and sharing.
Stephan Gerhard+2 more
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Multi-scale community organization of the human structural connectome and its relationship with resting-state functional connectivity [PDF]
Richard F Betzel+2 more
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Neuroimaging Clinics of North America, 2022
A central tenet of modern neuroscience is the conceptualization of the brain as a collection of complex networks or circuits with a shift away from traditional "localizationist" theories. Connectomics seeks to unravel these brain networks and their role in the pathophysiology of neurologic diseases.
Erik H, Middlebrooks, Sanjeet S, Grewal
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A central tenet of modern neuroscience is the conceptualization of the brain as a collection of complex networks or circuits with a shift away from traditional "localizationist" theories. Connectomics seeks to unravel these brain networks and their role in the pathophysiology of neurologic diseases.
Erik H, Middlebrooks, Sanjeet S, Grewal
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Introduction Connectome analysis of the human brain's structural and functional architecture provides a unique opportunity to understand the organization of the brain's functional architecture.
X Wang, Ying-chia Lin, Steven H Baete
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Functional neurology, 2013
One of the most fascinating challenges in neuroscience is the reconstruction of the connectivity map of the brain. Recent years have seen a rapid expansion in the field of connectomics, whose aim is to trace this map and understand its relationship with neural computation.
SILVESTRI, LUDOVICO+2 more
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One of the most fascinating challenges in neuroscience is the reconstruction of the connectivity map of the brain. Recent years have seen a rapid expansion in the field of connectomics, whose aim is to trace this map and understand its relationship with neural computation.
SILVESTRI, LUDOVICO+2 more
openaire +4 more sources
Current Opinion in Psychiatry, 2015
The neural connections, interconnections and organized networks of the central nervous system (CNS), which represent the human connectome, are critical for intact brain function. Consequently, disturbances at any level or juncture of these networks may alter behaviour and/or lead to brain dysfunction.
Katherine L. Narr, Amber M. Leaver
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The neural connections, interconnections and organized networks of the central nervous system (CNS), which represent the human connectome, are critical for intact brain function. Consequently, disturbances at any level or juncture of these networks may alter behaviour and/or lead to brain dysfunction.
Katherine L. Narr, Amber M. Leaver
openaire +3 more sources
Human brain networks function in connectome-specific harmonic waves [PDF]
Selen Atasoy, Joel Pearson
exaly +2 more sources
e-Neuroforum, 2016
Abstract When trying to gain intuitions about the computations implemented in neural circuits, we often use comparisons with electronic circuits. However, one fundamental difference to hard-wired electronic circuits is that the structure of neural circuits undergoes constant remodeling.
Jochen Triesch+2 more
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Abstract When trying to gain intuitions about the computations implemented in neural circuits, we often use comparisons with electronic circuits. However, one fundamental difference to hard-wired electronic circuits is that the structure of neural circuits undergoes constant remodeling.
Jochen Triesch+2 more
openaire +2 more sources
Connectomics of neurodegeneration
Nature Neuroscience, 2019Misfolded protein aggregates are a classical hallmark of many neurodegenerative diseases. By combining a mouse model of misfolded protein injection and a brain network model of misfolded protein diffusion, a study now finds a strong link between the stereotypical spreading patterns of neurodegeneration, protein expression and anatomical connectivity.
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The pretectal connectome in lamprey
Journal of Comparative Neurology, 2016ABSTRACTIn vertebrates, the pretectum and optic tectum (superior colliculus in mammals) are visuomotor areas that process sensory information and shape motor responses. Whereas the tectum has been investigated in great detail, the pretectum has received far less attention.
Capantini, Lorenza+3 more
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