Results 21 to 30 of about 52,544 (272)
Dysfunction of the Hippocampal-Lateral Septal Circuit Impairs Risk Assessment in Epileptic Mice
Frontiers in Molecular Neuroscience, 2022 Temporal lobe epilepsy, a chronic disease of the brain characterized by degeneration of the hippocampus, has impaired risk assessment. Risk assessment is vital for survival in complex environments with potential threats.
Yi Cao +12 more
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An Open MRI Dataset For Multiscale Neuroscience
Scientific Data, 2022 Measurement(s) Brain anatomy • Brain activity • Diffusion • Brain microstructure • Functional connectivity • Structural connectivity Technology Type(s) magnetic resonance imaging (MRI) • Functional Magnetic Resonance Imaging • Diffusion Weighted Imaging •
Jessica Royer +16 more
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BMC Biology, 2021 Background Although electrical stimulation of the peripheral and central nervous systems has attracted much attention owing to its potential therapeutic effects on neuropsychiatric diseases, its non-cell-type-specific activation characteristics may ...
Yi Cao +7 more
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Nature Methods, 2013 Opinions diverge on whether mapping the synaptic connectivity of the brain is a good idea. Here we argue that albeit their limitations, such maps will reveal essential characteristics of neural circuits that would otherwise be inaccessible.
Jeff W. Lichtman, Joshua L Morgan
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The connectome of an insect brain
Science, 2022 AbstractBrains contain networks of interconnected neurons, so knowing the network architecture is essential for understanding brain function. We therefore mapped the synaptic-resolution connectome of an insect brain (Drosophilalarva) with rich behavior, including learning, value-computation, and action-selection, comprising 3,013 neurons and 544,000 ...
Michael Winding +19 more
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Alternations and Applications of the Structural and Functional Connectome in Gliomas: A Mini-Review
Frontiers in Neuroscience, 2022 In the central nervous system, gliomas are the most common, but complex primary tumors. Genome-based molecular and clinical studies have revealed different classifications and subtypes of gliomas. Neuroradiological approaches have non-invasively provided
Ziyan Chen +8 more
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Cartography and Connectomes [PDF]
Neuron, 2013 The past 25 years have seen great progress in parcellating the cerebral cortex into a mosaic of many distinct areas in mice, monkeys, and humans. Quantitative studies of interareal connectivity have revealed unexpectedly many pathways and a wide range of connection strengths in mouse and macaque cortex. In humans, advances in analyzing "structural" and
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PLoS Biology, 2012 Connectivity determines the function of neural circuits. Historically, circuit mapping has usually been viewed as a problem of microscopy, but no current method can achieve high-throughput mapping of entire circuits with single neuron precision. Here we describe a novel approach to determining connectivity.
Zador, A. M. +5 more
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A morphospace of functional configuration to assess configural breadth based on brain functional networks [PDF]
, 2019 The best approach to quantify human brain functional reconfigurations in response to varying cognitive demands remains an unresolved topic in network neuroscience.
Abbas, Kausar +7 more
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The FASEB Journal, 2013 Connectional maps of the brain may have value in developing models of both how the brain works and how it fails when subsets of neurons or synapses are missing or misconnected. Such maps might also provide detailed information about how brain circuits develop and age. I am eager to obtain such maps in neonatal animals because of a longstanding interest
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