Results 301 to 310 of about 64,126 (335)

Brain network dynamics determine tau presence while regional vulnerability governs tau load in Alzheimer’s disease

Xiao Y, Spotorno N, An L, Bazinet V, Hansen JY, Strandberg O, Shafiei G, Behjat HH, Funck T, Salvadó G, Stomrud E, Smith R, Palmqvist S, Ossenkoppele R, Mattsson-Carlgren N, Palomero-Gallagher N, Dagher A, Misic B, Hansson O, Vogel JW.   +19 more
europepmc   +1 more source

Heterogeneity in human brain clearance adds resilience against tauopathy – a computational model informed by glymphatic MRI

Brennan GS, Thompson TB, Oliveri H, Vinje V, Ringstad G, Eide PK, Goriely A, Rognes ME.   +7 more
europepmc   +1 more source

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Brain Connectomics

Neuroimaging Clinics of North America, 2022
A central tenet of modern neuroscience is the conceptualization of the brain as a collection of complex networks or circuits with a shift away from traditional "localizationist" theories. Connectomics seeks to unravel these brain networks and their role in the pathophysiology of neurologic diseases.
Erik H, Middlebrooks, Sanjeet S, Grewal
openaire   +2 more sources

Mapping Multi-Modal Brain Connectome for Brain Disorder Diagnosis via Cross-Modal Mutual Learning

IEEE Transactions on Medical Imaging, 2023
Recently, the study of multi-modal brain connectome has recorded a tremendous increase and facilitated the diagnosis of brain disorders. In this paradigm, functional and structural networks, e.g., functional and structural connectivity derived from fMRI ...
Yanwu Yang, Chenfei Ye, Xutao Guo, Tao Wu, Yang Xiang, Tingxia Ma   +5 more
semanticscholar   +1 more source

The connectomics challenge.

Functional neurology, 2013
One of the most fascinating challenges in neuroscience is the reconstruction of the connectivity map of the brain. Recent years have seen a rapid expansion in the field of connectomics, whose aim is to trace this map and understand its relationship with neural computation.
SILVESTRI, LUDOVICO, SACCONI, LEONARDO, PAVONE, FRANCESCO SAVERIO   +2 more
openaire   +4 more sources

Connectome and schizophrenia

Current Opinion in Psychiatry, 2015
The neural connections, interconnections and organized networks of the central nervous system (CNS), which represent the human connectome, are critical for intact brain function. Consequently, disturbances at any level or juncture of these networks may alter behaviour and/or lead to brain dysfunction.
Katherine L. Narr, Amber M. Leaver
openaire   +3 more sources

Scale matters: The nested human connectome

Science, 2022
A comprehensive description of how neurons and entire brain regions are interconnected is fundamental for a mechanistic understanding of brain function and dysfunction.
M. Axer, K. Amunts
semanticscholar   +1 more source

Mapping Symptoms to Brain Networks with the Human Connectome.

New England Journal of Medicine, 2018
The Brain Connectome and New Methods of Lesion Analysis Complex neurologic and psychiatric syndromes cannot be understood on the basis of focal brain lesions.
M. Fox
semanticscholar   +1 more source

The dynamic connectome

e-Neuroforum, 2016
Abstract When trying to gain intuitions about the computations implemented in neural circuits, we often use comparisons with electronic circuits. However, one fundamental difference to hard-wired electronic circuits is that the structure of neural circuits undergoes constant remodeling.
Jochen Triesch, Simon Rumpel, Simon Rumpel   +2 more
openaire   +2 more sources

Connectomics of neurodegeneration

Nature Neuroscience, 2019
Misfolded protein aggregates are a classical hallmark of many neurodegenerative diseases. By combining a mouse model of misfolded protein injection and a brain network model of misfolded protein diffusion, a study now finds a strong link between the stereotypical spreading patterns of neurodegeneration, protein expression and anatomical connectivity.
openaire   +3 more sources