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Alternations and Applications of the Structural and Functional Connectome in Gliomas: A Mini-Review
In the central nervous system, gliomas are the most common, but complex primary tumors. Genome-based molecular and clinical studies have revealed different classifications and subtypes of gliomas. Neuroradiological approaches have non-invasively provided
Ziyan Chen+8 more
doaj +1 more source
The white matter connectome as an individualized biomarker of language impairment in temporal lobe epilepsy. [PDF]
ObjectiveThe distributed white matter network underlying language leads to difficulties in extracting clinically meaningful summaries of neural alterations leading to language impairment.
Bahrami, Naeim+10 more
core +2 more sources
Neural connectivity predicts spreading of alpha-synuclein pathology in fibril-injected mouse models: Involvement of retrograde and anterograde axonal propagation. [PDF]
In Parkinson's disease, some of the first alpha-synuclein aggregates appear in the olfactory system and the dorsal motor nucleus of the vagus nerve before spreading to connected brain regions.
Brundin, Patrik+3 more
core +2 more sources
CAVE: Connectome Annotation Versioning Engine
Advances in Electron Microscopy, image segmentation and computational infrastructure have given rise to large-scale and richly annotated connectomic datasets which are increasingly shared across communities. To enable collaboration, users need to be able
S. Dorkenwald+41 more
semanticscholar +1 more source
A Genetic Model of the Connectome [PDF]
The connectomes of organisms of the same species show remarkable architectural and often local wiring similarity, raising the question: where and how is neuronal connectivity encoded? Here, we start from the hypothesis that the genetic identity of neurons guides synapse and gap-junction formation and show that such genetically driven wiring predicts ...
Albert-László Barabási+3 more
openaire +4 more sources
Learning and comparing functional connectomes across subjects [PDF]
Functional connectomes capture brain interactions via synchronized fluctuations in the functional magnetic resonance imaging signal. If measured during rest, they map the intrinsic functional architecture of the brain.
Craddock, R. C., Varoquaux, Gaël
core +4 more sources
Graph theory in the last two decades penetrated sociology, molecular biology, genetics, chemistry, computer engineering, and numerous other fields of science.
Grolmusz, Vince+2 more
core +3 more sources
Cartography and Connectomes [PDF]
The past 25 years have seen great progress in parcellating the cerebral cortex into a mosaic of many distinct areas in mice, monkeys, and humans. Quantitative studies of interareal connectivity have revealed unexpectedly many pathways and a wide range of connection strengths in mouse and macaque cortex. In humans, advances in analyzing "structural" and
openaire +3 more sources
Connectomics of Human Electrophysiology
We present both a scientific overview and conceptual positions concerning the challenges and assets of electrophysiological measurements in the search for the nature and functions of the human connectome. We discuss how the field has been inspired by findings and approaches from functional magnetic resonance imaging (fMRI) and informed by a small ...
Sepideh Sadaghiani+2 more
openaire +5 more sources
Enhanced functional connectome of cerebellum in chronic insomnia patients
Background Functional abnormalities of the cerebellum have been found to be closely associated with chronic insomnia (CI). However, whether there are abnormalities in the topology of the functional connectome of the cerebellum in these patients is still ...
Shiqi Lin+6 more
doaj +1 more source