Results 51 to 60 of about 69,264 (321)

The white matter connectome as an individualized biomarker of language impairment in temporal lobe epilepsy. [PDF]

open access: yes, 2019
ObjectiveThe distributed white matter network underlying language leads to difficulties in extracting clinically meaningful summaries of neural alterations leading to language impairment.
Bahrami, Naeim   +10 more
core   +2 more sources

Connecting Connectomes to Physiology

open access: yesThe Journal of Neuroscience, 2023
With the advent of volumetric EM techniques, large connectomic datasets are being created, providing neuroscience researchers with knowledge about the full connectivity of neural circuits under study. This allows for numerical simulation of detailed, biophysical models of each neuron participating in the circuit. However, these models typically include
Alexander Borst, Christian Leibold
openaire   +4 more sources

Mapping hybrid functional-structural connectivity traits in the human connectome [PDF]

open access: yes, 2018
One of the crucial questions in neuroscience is how a rich functional repertoire of brain states relates to its underlying structural organization. How to study the associations between these structural and functional layers is an open problem that ...
Amico, Enrico, Goñi, Joaquín
core   +2 more sources

Connectomics of Human Electrophysiology

open access: yesNeuroImage, 2021
We present both a scientific overview and conceptual positions concerning the challenges and assets of electrophysiological measurements in the search for the nature and functions of the human connectome. We discuss how the field has been inspired by findings and approaches from functional magnetic resonance imaging (fMRI) and informed by a small ...
Sepideh Sadaghiani   +2 more
openaire   +4 more sources

Indole induces anxiety-like behaviour in mice mediated by brainstem locus coeruleus activation

open access: yesNeurobiology of Disease
The gut microbiota produces metabolites that enrich the host metabolome and play a part in host physiology, including brain functions. Yet the biological mediators of this gut-brain signal transduction remain largely unknown.
Hayatte-Dounia Mir   +10 more
doaj   +1 more source

Functional connectome predicting individual gait function and its relationship with molecular architecture in Parkinson's disease

open access: yesNeurobiology of Disease, 2023
Gait impairment is a common symptom of Parkinson's disease (PD), but its neural signature remains unclear due to the interindividual variability of gait performance.
Haoting Wu   +18 more
doaj   +1 more source

Disambiguating the role of blood flow and global signal with partial information decomposition [PDF]

open access: yes, 2019
Global signal (GS) is an ubiquitous construct in resting state functional magnetic resonance imaging (rs-fMRI), associated to nuisance, but containing by definition most of the neuronal signal.
Calhoun, Vince D.   +5 more
core   +2 more sources

Transforming descending input into motor output: An analysis of the Drosophila Male Adult Nerve Cord connectome

open access: yesbioRxiv
In most animals, a relatively small number of descending neurons (DNs) connect higher brain centers in the animal’s head to circuits and motor neurons (MNs) in the nerve cord of the animal’s body that effect movement of the limbs. To understand how brain
H. Cheong   +14 more
semanticscholar   +1 more source

Connectomics and epilepsy [PDF]

open access: yesCurrent Opinion in Neurology, 2013
Tremendous advances have occurred in recent years in elucidating basic mechanisms of epilepsy at the level of ion channels and neurotransmitters. Epilepsy, however, is ultimately a disease of functionally and/or structurally aberrant connections between neurons and groups of neurons at the systems level.
Jerome Engel   +6 more
openaire   +2 more sources

Whole-brain annotation and multi-connectome cell typing of Drosophila

open access: yesNature
The fruit fly Drosophila melanogaster has emerged as a key model organism in neuroscience, in large part due to the concentration of collaboratively generated molecular, genetic and digital resources available for it. Here we complement the approximately
P. Schlegel   +303 more
semanticscholar   +1 more source

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