Results 61 to 70 of about 69,264 (321)

Network Statistics of the Whole-Brain Connectome of Drosophila

bioRxiv, 2023
Brains comprise complex networks of neurons and connections. Network analysis applied to the wiring diagrams of brains can offer insights into how brains support computations and regulate information flow.
Albert Lin, Runzhe Yang, S. Dorkenwald, Arie Matsliah, A. Sterling, P. Schlegel, Szi-chieh Yu, Claire E. McKellar, Marta Costa, K. Eichler, A. S. Bates, N. Eckstein, Jan Funke, G. Jefferis, Mala Murthy   +14 more
semanticscholar   +1 more source

Sequencing the Connectome

PLoS Biology, 2012
Connectivity determines the function of neural circuits. Historically, circuit mapping has usually been viewed as a problem of microscopy, but no current method can achieve high-throughput mapping of entire circuits with single neuron precision. Here we describe a novel approach to determining connectivity.
Zador, A. M., Dubnau, J., Oyibo, H. K., Zhan, H., Cao, G., Peikon, I. D.   +5 more
openaire   +5 more sources

Multimodal precision MRI of the individual human brain at ultra-high fields

Scientific Data
Multimodal neuroimaging, in particular magnetic resonance imaging (MRI), allows for non-invasive examination of human brain structure and function across multiple scales.
Donna Gift Cabalo, Ilana Ruth Leppert, Risavarshni Thevakumaran, Jordan DeKraker, Youngeun Hwang, Jessica Royer, Valeria Kebets, Shahin Tavakol, Yezhou Wang, Yigu Zhou, Oualid Benkarim, Nicole Eichert, Casey Paquola, Julien Doyon, Christine Lucas Tardif, David Rudko, Jonathan Smallwood, Raul Rodriguez-Cruces, Boris C. Bernhardt   +18 more
doaj   +1 more source

Longitudinal development of the human white matter structural connectome and its association with brain transcriptomic and cellular architecture

Communications Biology, 2023
From childhood to adolescence, the spatiotemporal development pattern of the human brain white matter connectome and its underlying transcriptomic and cellular mechanisms remain largely unknown.
Guozheng Feng, Rui Chen, Rui Zhao, Yuanyuan Li, Leilei Ma, Yanpei Wang, Weiwei Men, Jiahong Gao, Shuping Tan, Jian Cheng, Yong He, Shaozheng Qin, Qi Dong, Sha Tao, Ni Shu   +14 more
doaj   +1 more source

Dwelling Quietly in the Rich Club: Brain Network Determinants of Slow Cortical Fluctuations

, 2015
For more than a century, cerebral cartography has been driven by investigations of structural and morphological properties of the brain across spatial scales and the temporal/functional phenomena that emerge from these underlying features.
Breakspear, Michael, Gollo, Leonardo L., Heuvel, Martijn van den, Hutchison, R. Matthew, Zalesky, Andrew   +4 more
core   +1 more source

The α-Synuclein Origin and Connectome Model (SOC Model) of Parkinson’s Disease: Explaining Motor Asymmetry, Non-Motor Phenotypes, and Cognitive Decline

Journal of Parkinson's Disease, 2021
A new model of Parkinson’s disease (PD) pathogenesis is proposed, the α-Synuclein Origin site and Connectome (SOC) model, incorporating two aspects of α-synuclein pathobiology that impact the disease course for each patient: the anatomical location of ...
P. Borghammer
semanticscholar   +1 more source

Parameterizable consensus connectomes from the Human Connectome Project: the Budapest Reference Connectome Server v3.0 [PDF]

Cognitive Neurodynamics, 2016
Connections of the living human brain, on a macroscopic scale, can be mapped by a diffusion MR imaging based workflow. Since the same anatomic regions can be corresponded between distinct brains, one can compare the presence or the absence of the edges, connecting the very same two anatomic regions, among multiple cortices.
Balázs Szalkai, Csaba Kerepesi, Bálint Varga, Vince Grolmusz   +3 more
openaire   +5 more sources

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

Large language models improve clinical decision making of medical students through patient simulation and structured feedback: a randomized controlled trial

BMC Medical Education
Background Clinical decision-making (CDM) refers to physicians’ ability to gather, evaluate, and interpret relevant diagnostic information. An integral component of CDM is the medical history conversation, traditionally practiced on real or simulated ...
Emilia Brügge, Sarah Ricchizzi, Malin Arenbeck, Marius Niklas Keller, Lina Schur, Walter Stummer, Markus Holling, Max Hao Lu, Dogus Darici   +8 more
doaj   +1 more source

Robustness of connectome harmonics to local gray matter and long-range white matter connectivity changes

NeuroImage, 2021
Recently, it has been proposed that the harmonic patterns emerging from the brain's structural connectivity underlie the resting state networks of the human brain.
Sébastien Naze, Timothée Proix, Selen Atasoy, James R. Kozloski   +3 more
doaj   +1 more source