Results 71 to 80 of about 64,126 (335)
Journal of Parkinson's Disease, 2021 A new model of Parkinson’s disease (PD) pathogenesis is proposed, the α-Synuclein Origin site and Connectome (SOC) model, incorporating two aspects of α-synuclein pathobiology that impact the disease course for each patient: the anatomical location of ...
P. Borghammer
semanticscholar +1 more source
Disambiguating the role of blood flow and global signal with partial information decomposition [PDF]
, 2019 Global signal (GS) is an ubiquitous construct in resting state functional magnetic resonance imaging (rs-fMRI), associated to nuisance, but containing by definition most of the neuronal signal.
Calhoun, Vince D. +5 more
core +2 more sources
Data leakage inflates prediction performance in connectome-based machine learning models
Nature CommunicationsPredictive modeling is a central technique in neuroimaging to identify brain-behavior relationships and test their generalizability to unseen data. However, data leakage undermines the validity of predictive models by breaching the separation between ...
M. Rosenblatt +4 more
semanticscholar +1 more source
Parameterizable consensus connectomes from the Human Connectome Project: the Budapest Reference Connectome Server v3.0 [PDF]
Cognitive Neurodynamics, 2016 Connections of the living human brain, on a macroscopic scale, can be mapped by a diffusion MR imaging based workflow. Since the same anatomic regions can be corresponded between distinct brains, one can compare the presence or the absence of the edges, connecting the very same two anatomic regions, among multiple cortices.
Csaba Kerepesi +4 more
openaire +5 more sources
Multimodal precision MRI of the individual human brain at ultra-high fields
Scientific DataMultimodal neuroimaging, in particular magnetic resonance imaging (MRI), allows for non-invasive examination of human brain structure and function across multiple scales.
Donna Gift Cabalo +18 more
doaj +1 more source
Decoupling of brain function from structure reveals regional behavioral specialization in humans
, 2019 The brain is an assembly of neuronal populations interconnected by structural pathways. Brain activity is expressed on and constrained by this substrate.
Preti, Maria Giulia +1 more
core +1 more source
Brain networks under attack : robustness properties and the impact of lesions [PDF]
, 2016 A growing number of studies approach the brain as a complex network, the so-called ‘connectome’. Adopting this framework, we examine what types or extent of damage the brain can withstand—referred to as network ‘robustness’—and conversely, which kind of ...
Aerts, Hannelore +3 more
core +2 more sources
Connectome-constrained networks predict neural activity across the fly visual system
NatureWe can now measure the connectivity of every neuron in a neural circuit1–9, but we cannot measure other biological details, including the dynamical characteristics of each neuron.
Janne K. Lappalainen +9 more
semanticscholar +1 more source
The Human Connectome: A Structural Description of the Human Brain
PLoS Comput. Biol., 2005 The connection matrix of the human brain (the human “connectome”) represents an indispensable foundation for basic and applied neurobiological research.
O. Sporns, G. Tononi, R. Kötter
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Reliable biomarkers are essential for tracking disease progression and advancing treatments for multiple system atrophy (MSA). In this study, we propose the MSA Atrophy Index (MSA‐AI), a novel composite volumetric measure to distinguish MSA from related disorders and monitor disease progression. Methods Seventeen participants with an
Paula Trujillo +11 more
wiley +1 more source