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Neuroimaging Clinics of North America, 2022
A central tenet of modern neuroscience is the conceptualization of the brain as a collection of complex networks or circuits with a shift away from traditional "localizationist" theories. Connectomics seeks to unravel these brain networks and their role in the pathophysiology of neurologic diseases.
Erik H, Middlebrooks, Sanjeet S, Grewal
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A central tenet of modern neuroscience is the conceptualization of the brain as a collection of complex networks or circuits with a shift away from traditional "localizationist" theories. Connectomics seeks to unravel these brain networks and their role in the pathophysiology of neurologic diseases.
Erik H, Middlebrooks, Sanjeet S, Grewal
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Functional neurology, 2013
One of the most fascinating challenges in neuroscience is the reconstruction of the connectivity map of the brain. Recent years have seen a rapid expansion in the field of connectomics, whose aim is to trace this map and understand its relationship with neural computation.
SILVESTRI, LUDOVICO+2 more
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One of the most fascinating challenges in neuroscience is the reconstruction of the connectivity map of the brain. Recent years have seen a rapid expansion in the field of connectomics, whose aim is to trace this map and understand its relationship with neural computation.
SILVESTRI, LUDOVICO+2 more
openaire +4 more sources
Current Opinion in Psychiatry, 2015
The neural connections, interconnections and organized networks of the central nervous system (CNS), which represent the human connectome, are critical for intact brain function. Consequently, disturbances at any level or juncture of these networks may alter behaviour and/or lead to brain dysfunction.
Katherine L. Narr, Amber M. Leaver
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The neural connections, interconnections and organized networks of the central nervous system (CNS), which represent the human connectome, are critical for intact brain function. Consequently, disturbances at any level or juncture of these networks may alter behaviour and/or lead to brain dysfunction.
Katherine L. Narr, Amber M. Leaver
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Incorporation of Brain Connectomics for Stereotactic Radiosurgery Treatment Planning
Operative Neurosurgery, 2023BACKGROUND AND IMPORTANCE: Neurosurgeons have integrated neuroanatomy-based tractography to avoid critical structures during dose planning. However, they have yet to integrate more comprehensive connectome networks for radiosurgical planning.
Sam Dayawansa+5 more
semanticscholar +1 more source
e-Neuroforum, 2016
Abstract When trying to gain intuitions about the computations implemented in neural circuits, we often use comparisons with electronic circuits. However, one fundamental difference to hard-wired electronic circuits is that the structure of neural circuits undergoes constant remodeling.
Jochen Triesch+2 more
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Abstract When trying to gain intuitions about the computations implemented in neural circuits, we often use comparisons with electronic circuits. However, one fundamental difference to hard-wired electronic circuits is that the structure of neural circuits undergoes constant remodeling.
Jochen Triesch+2 more
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Connectomics of neurodegeneration
Nature Neuroscience, 2019Misfolded protein aggregates are a classical hallmark of many neurodegenerative diseases. By combining a mouse model of misfolded protein injection and a brain network model of misfolded protein diffusion, a study now finds a strong link between the stereotypical spreading patterns of neurodegeneration, protein expression and anatomical connectivity.
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Altered brain activity in unipolar depression unveiled using connectomics
Nature Mental Health, 2023R. Cash+4 more
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Nature Methods, 2020
X-ray holographic nano-tomography is a promising complement to electron microscopy for connectomics studies.
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X-ray holographic nano-tomography is a promising complement to electron microscopy for connectomics studies.
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2016
Despite potentially hundreds of emotional response types all being grouped under the term emotion, differing neural networks (defined as recruited elements) are in play for differing emotional states. Neural networks are uniquely recruited depending on the strategy employed to modify the emotional state and the circumstances related to the arousal of ...
Lori Drucker Wasserman+1 more
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Despite potentially hundreds of emotional response types all being grouped under the term emotion, differing neural networks (defined as recruited elements) are in play for differing emotional states. Neural networks are uniquely recruited depending on the strategy employed to modify the emotional state and the circumstances related to the arousal of ...
Lori Drucker Wasserman+1 more
openaire +2 more sources