Results 51 to 60 of about 16,090 (228)
, 2019 Neural circuits can be reconstructed from brain images acquired by serial section electron microscopy. Image analysis has been performed by manual labor for half a century, and efforts at automation date back almost as far.
Lee, Kisuk +5 more
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Robust Nucleus Detection With Partially Labeled Exemplars
IEEE Access, 2019 Quantitative analysis of cell nuclei in microscopic images is an essential yet challenging source of biological and pathological information. The major challenge is accurate detection and segmentation of densely packed nuclei in images acquired under a ...
Linqing Feng +5 more
doaj +1 more source
Heliyon, 2022 Connectomics is an important field of neuroscience that examines how neurons are connected and form functional circuits that underly the brain's functions. Conventional tracers based on dye have led to great advances in mapping these connections, and now,
João Guilherme Tassoni Bortoloci +1 more
doaj +1 more source
, 2018 Developing whole-brain emulation (WBE) technology would provide immense benefits across neuroscience, biomedicine, artificial intelligence, and robotics.
Collins, Logan Thrasher
core +1 more source
A connectomic approach to the lateral geniculate nucleus [PDF]
, 2017 Although the core functions and structure of the lateral geniculate nucleus (LGN) are well understood, this core is surrounded by questions about the integration of feedforward and feedback connections, interactions between different channels of ...
Morgan, Josh L
core +2 more sources
Connecting Connectomes to Physiology
The Journal of Neuroscience, 2023 With the advent of volumetric EM techniques, large connectomic datasets are being created, providing neuroscience researchers with knowledge about the full connectivity of neural circuits under study. This allows for numerical simulation of detailed, biophysical models of each neuron participating in the circuit. However, these models typically include
Alexander Borst, Christian Leibold
openaire +4 more sources
Nature Communications, 2017 Long term depression (LTD) of the cerebellum is known to be mediated by postsynaptic trafficking of glutamate receptor AMPAR. Here, Kim and colleagues show that early- to late-endosomal sorting of AMPAR represents the switch from expression to ...
Taegon Kim +2 more
doaj +1 more source
eLife, 2018 The labeling and identification of long-range axonal inputs from multiple sources within densely reconstructed electron microscopy (EM) datasets from mammalian brains has been notoriously difficult because of the limited color label space of EM. Here, we
Florian Drawitsch +3 more
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1st INCF Workshop on Genetic Animal Models for Brain Diseases [PDF]
, 2011 The INCF Secretariat organized a workshop to focus on the “role of neuroinformatics in the processes of building, evaluating, and using genetic animal models for brain diseases” in Stockholm, December 13–14, 2009.
Holm Graessner, Olaf Riess
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Place cells are more strongly tied to landmarks in deep than in superficial CA1
Nature Communications, 2017 Environmental cues affect the way mouse hippocampal place cells respond, but whether this information is integrated versus segregated in distinct hippocampal cell populations is unclear.
Tristan Geiller +3 more
doaj +1 more source