Results 81 to 90 of about 16,090 (228)

Virtual Fly Brain—An interactive atlas of the Drosophila nervous system

Frontiers in Physiology, 2023
As a model organism, Drosophila is uniquely placed to contribute to our understanding of how brains control complex behavior. Not only does it have complex adaptive behaviors, but also a uniquely powerful genetic toolkit, increasingly complete dense ...
Robert Court, Marta Costa, Marta Costa, Clare Pilgrim, Gillian Millburn, Alex Holmes, Alex McLachlan, Aoife Larkin, Nicolas Matentzoglu, Huseyin Kir, Helen Parkinson, Nicolas H. Brown, Cahir J. O’Kane, J. Douglas Armstrong, Gregory S. X. E. Jefferis, David Osumi-Sutherland   +15 more
doaj   +1 more source

Guided Proofreading of Automatic Segmentations for Connectomics

, 2017
Automatic cell image segmentation methods in connectomics produce merge and split errors, which require correction through proofreading. Previous research has identified the visual search for these errors as the bottleneck in interactive proofreading. To
Haehn, Daniel, Kaynig, Verena, Lichtman, Jeff W., Pfister, Hanspeter, Tompkin, James   +4 more
core   +1 more source

TWIK-1/TASK-3 heterodimeric channels contribute to the neurotensin-mediated excitation of hippocampal dentate gyrus granule cells

Experimental and Molecular Medicine, 2018
Nerve cell communication: Controlling excitation Inhibition of potassium channels by the hormone neurotensin (NT) increases the excitability of the dentate gyrus granule cells (DGGCs) of the hippocampus in the mouse brain. A study led by Jae-Yong Park at
Jae Hyouk Choi, Oleg Yarishkin, Eunju Kim, Yeonju Bae, Ajung Kim, Seung-Chan Kim, Kanghyun Ryoo, Chang-Hoon Cho, Eun Mi Hwang, Jae-Yong Park   +9 more
doaj   +1 more source

Effects of inhaled cannabis high in Δ9-THC or CBD on the aging brain: A translational MRI and behavioral study

Frontiers in Aging Neuroscience, 2023
With the recent legalization of inhaled cannabis for medicinal and recreational use, the elderly represents one of the newest, rapidly growing cohorts of cannabis users.
Aymen H. Sadaka, Justin Canuel, Marcelo Febo, Clare T. Johnson, Heather B. Bradshaw, Richard Ortiz, Federica Ciumo, Praveen Kulkarni, Michael A. Gitcho, Craig F. Ferris, Craig F. Ferris   +10 more
doaj   +1 more source

Synaptic partner prediction from point annotations in insect brains

, 2018
High-throughput electron microscopy allows recording of lar- ge stacks of neural tissue with sufficient resolution to extract the wiring diagram of the underlying neural network.
A Kreshuk, A Kreshuk, A Kreshuk, B Staffler, C Becker, N Kasthuri, O Ronneberger, S Dorkenwald, V Jagadeesh   +8 more
core   +1 more source

AI Alignment Versus AI Ethical Treatment: 10 Challenges

Analytic Philosophy, EarlyView.
ABSTRACT A morally acceptable course of AI development should avoid two dangers: creating unaligned AI systems that pose a threat to humanity and mistreating AI systems that merit moral consideration in their own right. This paper argues these two dangers interact and that if we create AI systems that merit moral consideration, simultaneously avoiding ...
Adam Bradley, Bradford Saad
wiley   +1 more source

DVID: Distributed Versioned Image-Oriented Dataservice

Frontiers in Neural Circuits, 2019
Open-source software development has skyrocketed in part due to community tools like github.com, which allows publication of code as well as the ability to create branches and push accepted modifications back to the original repository. As the number and
William T. Katz, Stephen M. Plaza
doaj   +1 more source

Desmosomal connectomics of all somatic muscles in an annelid larva

eLife, 2022
Cells form networks in animal tissues through synaptic, chemical, and adhesive links. Invertebrate muscle cells often connect to other cells through desmosomes, adhesive junctions anchored by intermediate filaments.
Sanja Jasek, Csaba Verasztó, Emelie Brodrick, Réza Shahidi, Tom Kazimiers, Alexandra Kerbl, Gáspár Jékely   +6 more
doaj   +1 more source

Annotating Synapses in Large EM Datasets [PDF]

, 2014
Reconstructing neuronal circuits at the level of synapses is a central problem in neuroscience and becoming a focus of the emerging field of connectomics.
Huang, Gary B., Olbris, Donald J., Parag, Toufiq, Plaza, Stephen M., Rivlin, Patricia K., Saunders, Mathew A.   +5 more
core  

Synaptic Partner Assignment Using Attentional Voxel Association Networks

, 2019
Connectomics aims to recover a complete set of synaptic connections within a dataset imaged by volume electron microscopy. Many systems have been proposed for locating synapses, and recent research has included a way to identify the synaptic partners ...
Ih, Dodam, Lee, Kisuk, Lu, Ran, Seung, H. Sebastian, Turner, Nicholas, Wu, Jingpeng   +5 more
core   +1 more source