Results 151 to 160 of about 308,175 (358)

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Survey, analysis and evaluation test on high voltage/current pulse transmission cables [PDF]

open access: yes
A survey, analysis, and testing of available cable connector configurations were carried out in connection with transmission of high voltage/current to an exploding wire bridge.
Dann, J. E., Ottzen, P. C.
core   +1 more source

A proposed adjustable RF cable connector [PDF]

open access: yes, 1973
In system that requires negligible loss, it may be necessary to adjust cable length to exact multiple of transmitted wavelength. Adjustable cable connector saves time and cost by eliminating need to add to or cut from cable.
Doyle, J. D., Stringer, E. J.
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Modified electrical connector [PDF]

open access: yes
A removable interfacial insulator design concept is described that simplifies electrical connector repairability when damage occurs to male electrical contacts or resilient interfacial ...
Yamamoto, S.
core   +1 more source

Pressure-welded flange assembly provides leaktight seal at reduced bolt loads [PDF]

open access: yes, 1966
Vibration resistant flange-connector assembly provides a leaktight seal under reduced bolt loads. The assembly consists of ductile metal plates that are pressure welded between dies mounted in recessed ...
Martenson, A. J.
core   +1 more source

Home - About - Disclaimer - Privacy