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Endothelial Connexin 37, Connexin 40, and Connexin 43 Respond Uniquely to Substrate and Shear Stress
Endothelium, 2007Endothelial connexins have been linked to atherosclerosis and hypertension; however, little is know about their sensitivity to stimuli and individual functions. This study investigates the responses of endothelial connexin 37, connexin 40, and connexin 43 (Cx37, Cx40, and Cx43) to shear stress and substrate.
Tiffany L, Johnson, Robert M, Nerem
openaire +2 more sources
2010
Non-healing cutaneous wounds such as leg ulcers are a major cause of morbidity and mortality, especially in diabetes. Currently 67% of ulcers fail to respond to treatment after 20 weeks of care, and are a substantial time and cost burden. Recent studies suggest significant increases in skin wound healing rates occur by reduction of connexin (Cx ...
Wright, Catherine, Martin, Patricia
openaire +1 more source
Non-healing cutaneous wounds such as leg ulcers are a major cause of morbidity and mortality, especially in diabetes. Currently 67% of ulcers fail to respond to treatment after 20 weeks of care, and are a substantial time and cost burden. Recent studies suggest significant increases in skin wound healing rates occur by reduction of connexin (Cx ...
Wright, Catherine, Martin, Patricia
openaire +1 more source
Trends in molecular medicine
Neuropathic pain is a chronic debilitating condition caused by nerve injury or a variety of diseases. At the core of neuropathic pain lies the aberrant neuronal excitability in the peripheral and/or central nervous system (PNS and CNS). Enhanced connexin expression and abnormal activation of connexin-assembled gap junctional channels are prominent in ...
Su, Yixun +2 more
openaire +1 more source
Neuropathic pain is a chronic debilitating condition caused by nerve injury or a variety of diseases. At the core of neuropathic pain lies the aberrant neuronal excitability in the peripheral and/or central nervous system (PNS and CNS). Enhanced connexin expression and abnormal activation of connexin-assembled gap junctional channels are prominent in ...
Su, Yixun +2 more
openaire +1 more source
Connexines et tandem-connexines cardiaques
Archives des Maladies du Coeur et des Vaisseaux - Pratique, 2006openaire +1 more source
Connexin-26 mutations in sporadic and inherited sensorineural deafness
Lancet, The, 1998Xavier Estivill +2 more
exaly