Results 151 to 160 of about 1,607,329 (285)

Tyrosine residues at the substrate binding site in human NQO1 homodimer: Protein conformational dynamics and optimization of substrate binding geometry

open access: yesThe FEBS Journal, EarlyView.
Human NAD(P)H:quinone oxidoreductase 1 is a homodimeric flavoenzyme crucial for redox metabolism and linked to significant health issues. Point mutations at Tyr126 and Tyr128 demonstrate their essential roles in optimizing substrate binding geometry for catalysis, as well as in half‐site reactivity and conformational dynamics during the enzyme's ...
Maribel Rivero   +8 more
wiley   +1 more source

Shedding light on the environmental efficiency of the public light service: minimising light pollution through the global Malmquist–Luenberger index

open access: yesInternational Transactions in Operational Research, EarlyView.
Abstract The search for evidence in public management and the implementation of good management by public bodies is becoming increasingly important, and the principles of effectiveness and efficiency should be reinforced. Therefore, this paper aims to analyse the change in efficiency in the provision of public lighting services by local governments ...
Pablo Povedano‐Fernández   +2 more
wiley   +1 more source

Conocimientos Tradicionales

open access: yes, 2016
El módulo presenta información acerca de los conocimientos tradicionales relacionados con la biodiversidad a fin de fomentar su revalorización y visibilizar su aporte al desarrollo. De manera específica, presenta definiciones, marco normativo, casos emblemáticos de protección de conocimientos tradicionales, desafíos actuales, entre otros aspectos.
Sumalavia, Daniel   +2 more
openaire   +1 more source

Evaluating Leadership and Teamwork Competency Acquisition Through Clinical Simulation: Development of the Clinical Simulation Learning Leadership and Teamwork Scale

open access: yesJournal of Clinical Nursing, EarlyView.
ABSTRACT Advanced simulation is a methodology that allows the development of technical skills and transversal skills such as teamwork and leadership. There are tools to measure the development of technical competencies and student satisfaction with the methodology, but not to measure the development and use of transversal competencies in the clinical ...
Rafael González‐Moret   +6 more
wiley   +1 more source

Using Cultural Theory to Specify the Policy Actors, Belief Systems, and Sources of Coalition, Conflict, Stability, and Change in Policy Advocacy Coalitions and Environmental Resource Policies

open access: yesPolicy Studies Journal, EarlyView.
ABSTRACT We use grid‐group cultural theory (CT) to specify underspecified aspects of the Advocacy Coalition Framework (ACF). Our theoretical synthesis of CT and the ACF provides, first, an exhaustive typology of policy actors and their cultural cognitive biases that entail, guide, and constrain policy core beliefs about problem definitions and ...
Metodi Sotirov, Brendon Swedlow
wiley   +1 more source

Entrevista a Juan Cristóbal Cobo Romani. La educación en el mundo digital

open access: yesVoces de la educación, 2019
En la presente entrevista, el doctor Cristóbal Cobo comenta sobre los retos de la educación en un mundo digital, donde la comunidad académica encuentra nuevas formas de enseñar y aprender, convirtiendo a la tecnología en aliada de estos procesos, todo ...
Marisol Esperanza Cipagauta Moyano
doaj  

Designing Integrated Policies for the Twin Transition: Challenges and Tradeoffs

open access: yesPolicy Studies Journal, EarlyView.
ABSTRACT Democratic governance faces the intertwined imperatives of managing the transformative risks and opportunities of digitalization, particularly stemming from artificial intelligence (AI), while achieving environmental sustainability within planetary boundaries.
Martino Maggetti
wiley   +1 more source

Relocalizar el conocimiento. ¿Qué es el conocimiento?

open access: yes, 2013
Fil: Haber, Alejandro. Universidad Nacional de Catamarca. Escuela de Arqueología; Argentina.
openaire   +1 more source

Impact of the Unified Protocol on Attenuated Psychotic Symptoms, Cognitive Biases and Cognitive Insight in Patients at Ultra High Risk (UHR) for Psychosis: Secondary Results of a Pilot Randomized Controlled Trial

open access: yesJournal of Clinical Psychology, Volume 82, Issue 6, Page 915-926, June 2026.
ABSTRACT Background and Hypothesis Ultra high risk (UHR) for psychosis can have different clinical trajectories but the remission rates are only 51.9% after 3 years of follow‐up. Deficits in metacognition are associated with severity of symptoms and poor response to treatment.
Trinidad Peláez   +6 more
wiley   +1 more source

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