Results 31 to 40 of about 27,235 (248)

EDITOR’S PICK: CONTEMPORARY USE OF INTRACORONARY IMAGING IN PERCUTANEOUS CORONARY INTERVENTION

open access: yesEuropean Medical Journal Cardiology, 2018
Since the first balloon angioplasty in 1977, remarkable advances in catheter-based technology have been achieved with the use of stents and intracoronary devices. However, despite these developments, visual assessment of a 2-dimensional lumenogram of the
Matthew E. Li Kam Wa, Robert T. Gerber
doaj  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Византийцы на Боспоре VI в. / The Byzantines on Bosporus at 6th century CE

open access: yesМатериалы по археологии и истории античного и средневекового Крыма, 2017
The article examines the history of the Byzantine conquest of the Cimmerian Bosporus in the 6th century CE. through the prism of the prosopographical approach.
Bolgov N.N.
doaj   +1 more source

Premières représentations du Huyapari (alias Orénoque) (1498-1552) : la quête de Meta et ses revers

open access: yesNuevo mundo - Mundos Nuevos, 2020
The great American rivers have been more obstacles than channels of communication for the Spanish or Portuguese conquerors. Their gigantism and the Amazonian natural environment with regard to the Amazon and the Orinoco, provoked a scrambled geographical
Louise Bénat-Tachot
doaj   +1 more source

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

open access: yesFEBS Letters, EarlyView.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji   +5 more
wiley   +1 more source

Contemporary Evidence, Treatment Strategies, and Indications for Chronic Total Occlusion-Percutaneous Coronary Intervention

open access: yesEuropean Medical Journal, 2017
Chronic total occlusions (CTOs) are detected incidentally in ˜20% of patients undergoing coronary angiography and are often associated with significant morbidity and mortality. CTOs can manifest with worsening symptoms, reduced left ventricular function,
Deshan Weeraman   +2 more
doaj  

On the Sarmatian Conquest of Scythia

open access: yesНижневолжский археологический вестник, 2018
The chronotope of Scythia conquest is one of the main issues of archaeology and history of the Scythian and Sarmatian Age. The literature sources present four versions of reasons and events, which led to the desintegration of Scythia in the 3rd century ...
Aleksandr V. Simonenko
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

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