Results 111 to 120 of about 49,253 (329)

Gram‐Scale Access to (3,11)‐Cyclotaxanes—Synthesis of 1‐Hydroxytaxuspine C

open access: yesAngewandte Chemie International Edition, EarlyView.
Belonging to the family of complex taxanes, 1‐hydroxytaxuspine C is a densely functionalized natural product. The synthesis was realized via a semisynthetic approach, starting from commercially available 10‐deacetylbaccatin III. A late‐stage photocyclization was utilized to install the characteristic transannular bond of complex taxanes, transforming ...
Philipp Schoch   +4 more
wiley   +1 more source

Local anesthesia with and without conscious sedation versus general anesthesia for oral surgical procedures in pediatric patients: a retrospective cross-sectional study [PDF]

open access: yesRevista Portuguesa de Estomatologia, Medicina Dentária e Cirurgia Maxilofacial
Objectives: To compare the effectiveness of general anesthesia versus local anesthesia with or without conscious sedation for minor oral surgery procedures in pediatric patients.
Ana López-Velasco   +4 more
doaj   +1 more source

Semantic primitives and compositionality: An Annual Review of Information Science and Technology (ARIST) paper

open access: yesJournal of the Association for Information Science and Technology, EarlyView.
Abstract The term semantic primitives refers to a set of basic, atomic concepts from which all other (compound) concepts are constructed. It presupposes the principle of compositionality—the idea that complex items or expressions can be formed by combining simpler constituents.
Birger Hjørland
wiley   +1 more source

Echocardiographic evaluation of velocity ratio, velocity time integral ratio, and pulmonary valve area in dogs with pulmonary valve stenosis. [PDF]

open access: yes, 2018
BackgroundVelocity ratio, velocity time integral (VTI) ratio, and pulmonary valve area indexed to body surface area (iPVA) are methods of assessment of pulmonary valve stenosis (PS) severity that are less dependent on blood flow. Studies evaluating these
Bélanger, Catherine   +5 more
core   +1 more source

Senkyunolide I Improves Septicemia‐Induced Brain Dysfunction via Regulating Nrf2 and Astrocyte Activity.

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Senkyunolide I (Sen I) has a protective effect on the blood–brain barrier (BBB) in rats with sepsis‐associated encephalopathy (SAE). This study investigated whether Sen I regulates Nrf2 to ameliorate sepsis‐induced brain dysfunction (SIBD). Sixty rats were randomly assigned into Sham group, SAE group (Model group), SAE + Sen I group (72 mg/kg,
Haohao Cao, Tao Liu, Meixia Xu
wiley   +1 more source

Medico-legal evaluation of the gynaecological consultation in cases of annulment presenting to the Ecclesiastical Tribunal of the Roman Curia in Malta [PDF]

open access: yes, 2013
The Ecclesiastical Tribune of the Roman Curia in Malta appoints gynaecologists as medical experts to certain cases seeking annulment. These cases often essentially revolve around the confirmation or exclusion of virginity but may involve requests for ...
Buttigieg, Gabrielle   +1 more
core  

Prescribing competence: The pros and cons of different methods for assessment

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Evaluating a medical graduate’s competence in rational prescribing is challenging. With the aim to guide and inspire teachers, this narrative review explores different methods that can be used to assess prescribing competence. Each method has its own advantages and disadvantages, and thus a mix of different assessment methods is needed throughout the ...
David J. Brinkman   +3 more
wiley   +1 more source

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