Results 121 to 130 of about 469,942 (310)

The structure of phenomenal consciousness [PDF]

open access: yes, 2015
Philosophers have largely abandoned the claim that the special sciences will ultimately reduce to microphysics in favour of the view that the special sciences trade in functional explanations. However, a careful examination of scientific practice reveals
Opie, J.   +3 more
core   +1 more source

The Gaze of Schizophrenia Patients Captured by Bottom-up Saliency

open access: yesSchizophrenia
Schizophrenia (SCHZ) notably impacts various human perceptual modalities, including vision. Prior research has identified marked abnormalities in perceptual organization in SCHZ, predominantly attributed to deficits in bottom-up processing.
Petr Adámek   +10 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Psychoactive Drugs and Alterations to Consciousness [PDF]

open access: yes, 2009
Altered states of consciousness (ASC) are difficult to define and previous attempts to do so have not been widely adopted. This is a problem inherent in defining consciousness in general. Theories that link ASC to neural substrates, such as the transient
Dietrich A., A. Dietrich
core   +1 more source

Consciousness and cosmos building an ontological framework [PDF]

open access: yes, 2018
Contemporary theories of consciousness are based on widely different concepts of its nature, most or all of which probably embody aspects of the truth about it. Starting with a concept of consciousness indicated by the phrase ‘the feeling of what happens’
Nixon, Greg   +3 more
core   +2 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Principles and practice of pain and suffering management with clinical hypnosis and meditative stages in the mind-body gap. [PDF]

open access: yes, 2013
This work will highlight the very best integration of our current knowledge regarding clinical hypnosis and meditative stages, as innovations in clinical practice such as the development of hypnotic suggestions based on new understanding of the ...
Brugnoli, Maria Paola, Siddharth Agarwal
core  

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Life, brain and consciousness : new perceptions through targeted systems analysis / [PDF]

open access: yes, 1990
The relation between mind and brain can never be understood by science until the nature of consciousness and self-consciousness is clearly perceived as specific system-properties.
Sommerhoff, Gerd.
core  

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