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Assessing consciousness and cognition in disorders of consciousness
NeuroRehabilitationDetecting willful cognition in these patients is known to be challenging due to the patients’ motor disabilities and high vigilance fluctuations but also due to the lack of expertise and use of adequate tools to assess these patients in specific settings.
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Neurology, 2014
Prolonged disorders of consciousness (DOC)—the vegetative and minimally conscious states (VS/MCS)—are uncommon but devastating outcomes after severe brain injury. Until recently, the medical community has viewed them with great pessimism with respect to both prognosis and effective treatments.
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Prolonged disorders of consciousness (DOC)—the vegetative and minimally conscious states (VS/MCS)—are uncommon but devastating outcomes after severe brain injury. Until recently, the medical community has viewed them with great pessimism with respect to both prognosis and effective treatments.
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Chronic disorders of consciousness
The Lancet, 2006The vegetative state and the minimally conscious state are disorders of consciousness that can be acute and reversible or chronic and irreversible. Diffuse lesions of the thalami, cortical neurons, or the white-matter tracts that connect them cause the vegetative state, which is wakefulness without awareness.
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Electrophysiology in disorders of consciousness
Electroencephalography (EEG) has emerged as a powerful tool in the diagnosis, characterization, and prognostication of patients with disorders of consciousness (DoC). EEG is a well-established monitoring tool for the treatment of specific patient populations with impaired consciousness, such as those with status epilepticus and cardiac arrest.Mohamed, Ridha +2 more
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[Neurology of consciousness and of consciousness disorders].
Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1994The two physiologic components of conscious behaviour, namely arousal (vigilance) and content of consciousness (presence of mind), may be affected differently, depending on the type and distribution of the underlying brain disease. Disturbance of arousal primarily affects wakefulness and awareness and leads to obtundation, stupor and coma.
C W, Hess, C, Bassetti
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Spontaneous eye blinking as a diagnostic marker in prolonged disorders of consciousness
Scientific Reports, 2021Anna Estraneo +2 more
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The neuroethics of disorders of consciousness: a brief history of evolving ideas
Brain, 2021Robert Truog +2 more
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Recovery from disorders of consciousness: mechanisms, prognosis and emerging therapies
Nature Reviews Neurology, 2020Brian L Edlow, Jan Claassen
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Treatment Trials in Disorders of Consciousness: Challenges and Future Directions
Brain Sciences, 2022John Whyte
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