Results 21 to 30 of about 224,273 (291)

Élaborer un test d’intérêts pour l’auto-orientation : problèmes de conception, de validation et d’utilisation

open access: yesMesure et Évaluation en Éducation, 1999
Pour qu’un sujet puisse s’auto-orienter, il doit pouvoir disposer d’un instrument d’évaluation directement interprétable et qui soit de valeur métrologique assurée. Ces deux thèses sont illustrées par l’exemple du questionnaire QIPOS.
Daniel Bain, Jean Cardinet
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Evaluation of porcine reproductive and respiratory syndrome stabilization protocols in 23 French Farrow-to-finish farms located in a high-density swine area

open access: yesPorcine Health Management, 2017
Background Porcine reproductive and respiratory syndrome virus (PRRSV) is responsible for reproductive disorders in sows and respiratory problems in pigs, and has a major economic impact.
Pauline Berton   +5 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Electrochemical Behavior of Flame‐Sprayed Sc‐Doped AlCoCrFeMo High‐Entropy Alloy Coatings in 3.5% Sodium Chloride Solution

open access: yesAdvanced Engineering Materials, EarlyView.
Scandium (Sc)‐doped AlCoCrFeMo HEA coatings are fabricated via flame spraying with 0.1, 0.3, and 0.5 wt% Sc additions. Among these, the HEA‐Sc0.3 coating exhibits the highest corrosion resistance, indicated by a more positive corrosion potential and lower current density.
Pankaj Kumar   +7 more
wiley   +1 more source

Conseil de sécurité des nations unies face à la situation sécuritaire à l’Est de la République Démocratique du Congo. Critiques et Perspectives

open access: yesRevue Congolaise des Sciences et Technologies
Face à la crise sécuritaire persistante dans l'est de la RDC, marquée par l'expansion du M23 et la dégradation humanitaire, le conseil de sécurité des Nations Unies condamne le soutien extérieur au M23 (notamment le Rwanda) et exige un désengagement ...
Gilbert Minga Kwete   +3 more
doaj   +1 more source

Printed Integrated Logic Circuits Based on Chitosan‐Gated Organic Transistors for Future Edible Systems

open access: yesAdvanced Functional Materials, EarlyView.
Edible electronics needs integrated logic circuits for computation and control. This work presents a potentially edible printed chitosan‐gated transistor with a design optimized for integration in circuits. Its implementation in integrated logic gates and circuits operating at low voltage (0.7 V) is demonstrated, as well as the compatibility with an ...
Giulia Coco   +8 more
wiley   +1 more source

Quels dispositifs de conseil pour l’agriculture familiale marocaine ? Réflexions pour une démarche de conception des dispositifs de conseil. [PDF]

open access: yesAlternatives Rurales, 2014
Dans le cadre de sa politique agricole actuelle structurée autour du Plan Maroc vert, L’Etat a engagé une réforme en profondeur du conseil agricole, service qui était essentiellement assuré par les Centres des Travaux et les Centres de Mise en Valeur. La
Patrick Dugué   +2 more
doaj  

Mandatory vaccination of infants in France: Is that the way forward?

open access: yesEuropean Journal of General Practice, 2019
In this opinion paper, the authors argue that the extension of mandatory immunization of infants up to two years of age from three diseases (diphtheria, tetanus, poliomyelitis) to 11 diseases, introduced in France in January 2018, is not a sustainable ...
Henri Partouche   +3 more
doaj   +1 more source

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