Results 221 to 230 of about 1,467,463 (316)

Recognition of a Critical Functional Domain and Improved <i>PHOX2B</i> Missense Variant Interpretation by Utilization of In Silico Prediction Tools. [PDF]

Hum Mutat
Drackley A, Skol AD, Rand CM, Weese-Mayer DE, Yap KL.   +4 more
europepmc   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Reaching consensus on the definition of modifiable determinants of health: a Delphi study. [PDF]

BMJ Public Health
Stannard S, Alipio K, Berrington A, Paranjothy S, Hoyle RB, Owen RK, Fraser SD, Holland E, Alwan NA.   +8 more
europepmc   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Good Clinical Practices for the Management of Post-Stroke Spasticity with BoNT-A: A Delphi-Based Approach from the Italian Expert Group. [PDF]

Toxins (Basel)
Baricich A, Chisari C, De Blasiis P, Millevolte M, Picelli A, Santamato A, Caglioni PM, Molteni F.   +7 more
europepmc   +1 more source

Diels‐Alder Click Chemistry as a Dynamic‐Covalent Crosslinking Method in Spheroid‐Encapsulating Hydrogels for Cartilage Engineering

Advanced Healthcare Materials, EarlyView.
This research shows the development of hydrogels with Diels‐Alder click chemistry for engineering cartilage‐like tissue. The hydrogels support cartilage spheroids which could be cultured for at least 28 days. Furthermore, the spheroids showed a tendency to fuse together into a more consistent construct, and produced important components needed for ...
Sanne M. van de Looij, Antonia G. Vasilopoulou, Lennard Spauwen, Antoinette van den Dikkenberg, Jasmijn V. Korpershoek, Mylene de Ruijter, Jos Malda, Bas G. P. van Ravensteijn, Tina Vermonden   +8 more
wiley   +1 more source

Application of the far-lateral approach in uni-portal non-coaxial spinal endoscopic surgery: an evidence-based and Delphi consensus approach among Chinese expert opinions. [PDF]

Brain Spine
Yin M, Lin Y, Yu P, Wang D, Li F, Hao S, Sun K, Li K, Liu Y, Zhang X, Li J, Wang M, Ma J, Yu W, Xue L, Li Z, Gao G, Zhang B, Xu B, Feng J, Chen C, Yan Y, Zhou J, Jing Y, Pei L, Cong Y, Li D, Zhang G, Shen S, Li Z, Cheng P, Zhang W, Zhang B, Wu D, Qu Y, Song E, Wang S.   +36 more
europepmc   +1 more source

Engineered Protein‐Based Ionic Conductors for Sustainable Energy Storage Applications

Advanced Materials, EarlyView.
Rational incorporation of charged residues into an engineered, self‐assembling protein scaffold yields solid‐state protein films with outstanding ionic conductivity. Salt‐doping further enhances conductivity, an effect amplified in the engineered variants. These properties enable the material integration into an efficient supercapacitor.
Juan David Cortés‐Ossa, Paolo Blesio, Marcial Fernandez‐Castro, Lisa Almonte, Maxence Fernandez, Mantas Liutkus, Perumal Pandurangan, Carlos Sabater, Aitor Villaverde, Manuel Melle‐Franco, Nurit Ashkenasy, Felipe Jiménez‐Ángeles, M. Carmen Morant‐Miñana, M. Reyes Calvo, Aitziber L. Cortajarena   +14 more
wiley   +1 more source

Management of metallo-β-lactamase-producing Enterobacterales infections: a modified Delphi study. [PDF]

JAC Antimicrob Resist
Carmeli Y, Price M, Daikos GL, Falcone M, Gales AC, Hagel S, Omrani AS, Ramirez P, Todi S, Wang M, Gheorghe M, Hauber B, Little CJ, Townsend A.   +13 more
europepmc   +1 more source