Results 281 to 290 of about 4,259,195 (377)

Classification criteria for Sjögren's syndrome: a revised version of the European criteria proposed by the American-European Consensus Group

open access: yesAnnals of the Rheumatic Diseases, 2002
C. Vitali   +12 more
semanticscholar   +1 more source

Dual‐Locking the SARS‐CoV‐2 Spike Trimer: An Amphipathic Molecular “Bolt” Stabilizes Conserved Druggable Interfaces for Coronavirus Inhibition

open access: yesAdvanced Science, EarlyView.
A new amphipathic molecule, S416 is discovered, that locks the SARS‐CoV‐2 spike protein in its closed state, blocking viral entry. S416 acts as a molecular bolt, binding six sites: three between adjacent RBDs and three connecting NTDs to RBDs. This dual‐locking mechanism stiffens the spike structure and reduces its flexibility.
Shiliang Li   +21 more
wiley   +1 more source

Pain management in preterm infants with necrotizing enterocolitis: an international expert consensus statement. [PDF]

open access: yesEur J Pediatr
Ten Barge JA   +37 more
europepmc   +1 more source

Management of Helicobacter pylori infection—the Maastricht V/Florence Consensus Report

open access: yesGut, 2016
P. Malfertheiner   +17 more
semanticscholar   +1 more source

Immunotyping the Tumor Microenvironment Reveals Molecular Heterogeneity for Personalized Immunotherapy in Cancer

open access: yesAdvanced Science, EarlyView.
This study develops TMEclassifier, a machine‐learning tool that classifies cancers into three distinct subtypes—Immune exclusive (IE), immune suppressive (IS), and immune activated (IA)—which exhibit significant heterogeneity and necessitate customized therapeutic strategies.
Dongqiang Zeng   +27 more
wiley   +1 more source

Expert Consensus on the Use of Diphenhydramine for Short-Term Insomnia: Efficacy, Safety, and Clinical Applications. [PDF]

open access: yesJ Clin Med
Ariza-Salamanca DF   +5 more
europepmc   +1 more source

Leucine‐Rich Repeat‐Containing G Protein‐Coupled Receptor 6 Ameliorates Pressure Overload‐Induced Cardiac Hypertrophy by Regulating Cardiomyocyte Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
LGR6 overexpression ameliorates cardiac hypertrophy by regulating metabolic reprogramming through USP4‐PPARα pathway. Abstract Metabolic reprogramming is a pivotal mechanism in the pathogenesis of pathological cardiac hypertrophy. Leucine‐rich repeat‐containing G protein‐coupled receptor 6 (Lgr6) has emerged as a significant player in cardiovascular ...
Mengmeng Zhao   +7 more
wiley   +1 more source

Approach to Lung Transplantation in Pulmonary Arterial Hypertension: A Delphi Consensus on Behalf of the Transplant Task Force of the Pulmonary Vascular Research Institute. [PDF]

open access: yesPulm Circ
Kolaitis NA   +29 more
europepmc   +1 more source

International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)

open access: yesJournal of Thrombosis and Haemostasis, 2006
S. Miyakis   +14 more
semanticscholar   +1 more source

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