Results 61 to 70 of about 600,349 (318)

Distributed Change Detection via Average Consensus over Networks

, 2019
Distributed change-point detection has been a fundamental problem when performing real-time monitoring using sensor-networks. We propose a distributed detection algorithm, where each sensor only exchanges CUSUM statistic with their neighbors based on the
AG Tartakovsky, AK Sahu, ES Page, G Fellouris, G Karagiannis, L Xiao, M Ludkovski, O Hadjiliadis, S Boyd, V Raghavan, VV Buldygin, Y Mei, Y Xie   +12 more
core   +1 more source

Novel adaptive genetic algorithm sample consensus [PDF]

Applied Soft Computing, 2019
Random sample consensus (RANSAC) is a successful algorithm in model fitting applications. It is vital to have strong exploration phase when there are an enormous amount of outliers within the dataset. Achieving a proper model is guaranteed by pure exploration strategy of RANSAC. However, finding the optimum result requires exploitation.
Shojaedini, Ehsan, Majd, Mahshid, Safabakhsh, Reza   +2 more
openaire   +2 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Equity decentralized consensus algorithm based on incentive compatibility

Tongxin xuebao, 2022
The PoW consensus algorithm has been proved to be incentive incompatible, existing computing centralization under high reward differences and slow convergence of forks in extreme cases.Based on this, an incentive-compatiblebased consensus algorithm SSPoW
Youliang TIAN, Yansen YUAN, Hongfeng GAO, Yang YANG, Jinbo XIONG   +4 more
doaj  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Gain-scheduled synchronization of parameter varying systems via relative $H_\infty$ consensus with application to synchronization of uncertain bilinear systems

, 2014
The paper considers a problem of consensus-based synchronization of uncertain parameter varying multi-agent systems. We present a method for constructing consensus-based synchronization protocol schedules for each agent to ensure it synchronizes with a ...
Ugrinovskii, V.
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Improved PBFT algorithm for high-frequency trading scenarios of alliance blockchain

Scientific Reports, 2022
With the continuous development of blockchain technology, the application scenarios of alliance blockchain are also increasing. The consensus algorithm can achieve distributed consensus among nodes in the network.
Song Tang, Zhiqiang Wang, Jian Jiang, Suli Ge, GaiFang Tan   +4 more
doaj   +1 more source

An Improved Approximate Consensus Algorithm in the Presence of Mobile Faults

, 2017
This paper explores the problem of reaching approximate consensus in synchronous point-to-point networks, where each pair of nodes is able to communicate with each other directly and reliably.
A Jadbabaie, D Dolev, F Bonnet, I Abraham, I Schizas, JA Garay, L Lamport, L Tseng, NA Lynch, RM Kieckhafer, T Sasaki   +10 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source