Results 211 to 220 of about 1,737,554 (259)

Albuminuria as a diagnostic criterion and a therapeutic target in heart failure and other cardiovascular disease

open access: yesEuropean Journal of Heart Failure, EarlyView.
The value of uACR. CKD, chronic kidney disease; CVD, cardiovascular disease; eGFR, estimated glomerular filtration rate; uACR, urine albumin‐to‐creatinine ratio. Abstract The high disease burden and bidirectional relationship of chronic kidney disease (CKD), heart failure (HF) and other cardiovascular disease (CVD) necessitate the need for early ...
Biykem Bozkurt   +2 more
wiley   +1 more source

Effect of pulmonary artery pressure‐guided management on outcomes of patients with heart failure outside clinical trials: A systematic review and meta‐analysis of real‐world evidence with the CardioMEMS Heart Failure System

open access: yesEuropean Journal of Heart Failure, EarlyView.
Meta‐analysis on the main outcomes of pulmonary artery pressure (PAP)‐guided management with the CardioMEMS Heart Failure (HF) System in patients with HF outside clinical trials. Effect measures are expressed as pooled means (95% CI), mean differences (95% CI), or pooled incidence rate ratios (95% CI), as appropriate.
Chris J. Kapelios   +4 more
wiley   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons   +17 more
wiley   +1 more source

Mental disorders and excess mortality: a systematic review protocol. [PDF]

open access: yesBMJ Open
Quirk SE   +8 more
europepmc   +1 more source

Consensus findings of an International Workshops on Genotoxicity Testing workshop on using transcriptomic biomarkers to predict genotoxicity

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Gene expression biomarkers have the potential to identify genotoxic and non‐genotoxic carcinogens, providing opportunities for integrated testing and reducing animal use. In August 2022, an International Workshops on Genotoxicity Testing (IWGT) workshop was held to critically review current methods to identify genotoxicants using ...
Roland Froetschl   +14 more
wiley   +1 more source

Policy entrepreneurship for transformative governance

open access: yesEuropean Policy Analysis, EarlyView.
Abstract Scholarship is growing on societal transitions, describing radical societal change involving multiple sectors and scales, and transformative governance, describing how public, private, and civil society actors use tools of policy to pursue this fundamental change, aiming to build resiliency and sustainability.
Gwen Arnold   +4 more
wiley   +1 more source

Risk predictors of severe adverse maternal outcomes in pre-eclampsia: a systematic review and meta-analysis protocol. [PDF]

open access: yesBMJ Open
Dasari H   +11 more
europepmc   +1 more source

Constructing the “moralization shock”: The role of contingency in the translation of anticorruption policy in France

open access: yesEuropean Policy Analysis, EarlyView.
Abstract This article applies the concept of transaction to the process of policy transfer, through the case of conflict of interest regulation in France, using archives, documentary sources, and interviews with stakeholders. It contributes to the literature on policy translation by clarifying the role of contingency, which remains underspecified.
Sofia Wickberg
wiley   +1 more source

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