Results 21 to 30 of about 1,737,554 (259)

Citizen participation and awareness raising in coastal protected areas. A case study from Italy [PDF]

, 2014
In this chapter, part of the research carried out within the SECOA project (www.projectsecoa.eu) is presented. Attention is devoted to methods and tools used for supporting the participatory process in a case of environmental conflict related to the ...
S. Di Zio, STANISCIA, BARBARA
core   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

Consensus Development at NIH: What Went Wrong [PDF]

, 1993
A close observer identifies the Science Court concept as inspiring consensus development conferences at the National Institutes of Health and describes the extent to which they have followed the model. Professor Jacoby also argues that, if the model were
Jacoby, Itzhak
core   +1 more source

Health-related preferences of older patients with multimorbidity: the protocol for an evidence map [PDF]

, 2019
Introduction: Interaction of conditions and treatments, complicated care needs and substantial treatment burden make patient–physician encounters involving multimorbid older patients highly complex.
Blom, Jeanet, Gerlach, Ferdinand M, González-González, Ana Isabel, Hoffmann, Tammy, Meerpohl, Joerg J, Muth, Christiane, Nguyen, Truc Sophia, Nothacker, Julia, Röttger, Kristian, Schmucker, Christine, Straus, Sharon E, van den Akker, Marjan, Wegwarth, Odette   +12 more
core   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

The Art of Knowledge Exchange: A Results-Focused Planning Guide for Development Practitioners [PDF]

, 2012
Designing and implementing knowledge exchange initiatives can be a big undertaking. This guide takes the guesswork out of the process by breaking it down into simple steps and providing tools to help you play a more effective role as knowledge connector ...
Aaron Leonard, Shobha Kumar
core  

Chaos Engineering For Understanding Consensus Algorithms Performance in Permissioned Blockchains [PDF]

arXiv, 2021
A critical component of any blockchain or distributed ledger technology (DLT) platform is the consensus algorithm. Blockchain consensus algorithms are the primary vehicle for the nodes within a blockchain network to reach an agreement. In recent years, many blockchain consensus algorithms have been proposed mainly for private and permissioned ...
arxiv  

Consensus statement from the international consensus meeting on post-traumatic cranioplasty

Acta Neurochirurgica, 2020
Due to the lack of high-quality evidence which has hindered the development of evidence-based guidelines, there is a need to provide general guidance on cranioplasty (CP) following traumatic brain injury (TBI), as well as identify areas of ongoing ...
C. Iaccarino, A. Kolias, P. D. Adelson, A. M. Rubiano, E. Viaroli, A. Buki, G. Cinalli, K. Fountas, T. Khan, S. Signoretti, V. Waran, A. O. Adeleye, R. Amorim, A. Bertuccio, A. Cama, R. Chesnut, P. De Bonis, A. Estraneo, A. Figaji, S. I. Florian, R. Formisano, P. Frassanito, C. Gatos, A. Germano, C. Giussani, I. Hossain, P. Kasprzak, F. La Porta, D. Lindner, A. Maas, W. Paiva, P. Palma, K. B. Park, P. Peretta, A. Pompucci, J. Posti, S. K. Sengupta, A. Sinha, V. Sinha, R. Stefini, G. Talamonti, A. Tasiou, G. Zona, M. Zucchelli, P. J. Hutchinson, F. Servadei   +45 more
semanticscholar   +1 more source

Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins

FEBS Open Bio, EarlyView.
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet, Julia Bartoli, Atakan Kabtan, Chloé M. Piras, Audrey C. Tempier, Eric Cascales, Julie P. Viala   +6 more
wiley   +1 more source

Application of Orthogonal Defect Classification for Software Reliability Analysis [PDF]

arXiv, 2022
The modernization of existing and new nuclear power plants with digital instrumentation and control systems (DI&C) is a recent and highly trending topic. However, there lacks strong consensus on best-estimate reliability methodologies by both the United States (U.S.) Nuclear Regulatory Commission (NRC) and the industry.
arxiv